SCHEMBL1669809

SCHEMBL1669809

Oc1cccc(N(Cc2ccccc2)c2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 5/20 0.51
OPRM1 P35372 3/20 0.51
OPRD1 P41143 3/20 0.51
LMNA P02545 2/20 0.51
MAPT P10636 2/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
HDAC1 Q13547 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
HTR7 P34969 3/20 0.46
ADRA1D P25100 2/20 0.46
ADRA1A P35348 2/20 0.46
ADRA1B P35368 2/20 0.46
HTR1A P08908 1/20 0.46
ADRA2A P08913 1/20 0.46
ADORA3 P0DMS8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9480221 0.98 OPRK1 (0.50) OPRK1OPRM1OPRD1LMNAMAPT
SCHEMBL1672672 0.83 CRHBP (0.58) OPRK1OPRM1OPRD1LMNAMAPT
SCHEMBL11514262 0.82 ESR1 (0.63) LMNAMAPTMEN1KMT2AALDH1A1
SCHEMBL918512 0.82 NR3C2 (0.56) ALDH1A1TSHRHDAC1HDAC8HDAC6
SCHEMBL11874481 0.80 ESR1 (0.66) MAPTMEN1KMT2AALDH1A1HDAC1
SCHEMBL10907115 0.80 ALDH1A1 (0.55) OPRK1OPRM1OPRD1LMNAMAPT
SCHEMBL9446230 0.80 NR3C2 (0.59) MEN1KMT2AALDH1A1TSHRHDAC1
Bromide SCHEMBL4613403 0.80 NR3C2 (0.55) ALDH1A1TSHRHDAC1HDAC8HDAC6
SCHEMBL1670400 0.79 ALDH1A1 (0.63) OPRK1OPRM1OPRD1LMNAMAPT
SCHEMBL14166018 0.79 PDK1 (0.57) OPRK1OPRM1OPRD1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2485900-B1 MULTICOLOUR THERMAL IMAGING MATERIAL ZINK IMAGING INC (US) 2014-05-21 EP disclosed
US-8372782-B2 Imaging system ZINK IMAGING, INC. (US) 2013-02-12 US disclosed
EP-2485900-A1 MULTICOLOUR THERMAL IMAGING MATERIAL Zink Imaging, Inc. (US) 2012-08-15 EP disclosed
EP-1597084-B1 IMAGING SYSTEM ZINK IMAGING LLC (US) 2012-04-11 EP disclosed
WO-2011044049-A1 MULTICOLOUR THERMAL IMAGING MATERIAL ZINK IMAGING, INC. (US) 2011-04-14 WO disclosed
US-20100099556-A1 Imaging System ZINK IMAGING, INC. 2010-04-22 US disclosed
US-20100016154-A1 IMAGING SYSTEM ZINK IMAGING, INC. 2010-01-21 US disclosed
US-7504360-B2 Imaging system ZINK IMAGING, INC. (US) 2009-03-17 US disclosed
US-20070123421-A1 Imaging system ZINK IMAGING, LLC. 2007-05-31 US disclosed
US-7176161-B2 Containing crystalline compounds which produce color when thermally converted to liquid or amorphous form time-independent ZINK IMAGING, LLC (US) 2007-02-13 US disclosed
US-20040176248-A1 Imaging system ZINK HOLDINGS LLC 2004-09-09 US disclosed