Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756450 | 0.76 | MGLL (0.36) | POLB | |
| SCHEMBL8903266 | 0.73 | MGLL (0.34) | — | |
| SCHEMBL8931853 | 0.72 | LMNA (0.31) | — | |
| SCHEMBL13533087 | 0.72 | MGLL (0.32) | — | |
| SCHEMBL13183261 | 0.71 | BRD4 (0.39) | — | |
| SCHEMBL18947917 | 0.71 | MGLL (0.31) | — | |
| SCHEMBL18510166 | 0.70 | GLA (0.41) | POLB | |
| SCHEMBL30779753 | 0.70 | GLA (0.41) | POLB | |
| SCHEMBL30699 | 0.70 | GLA (0.41) | POLB | |
| SCHEMBL352074 | 0.70 | CHRM1 (0.33) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2844258-B1 | METHODS AND COMPOSITIONS FOR TREATING BACTERIAL INFECTION | UNIV MICHIGAN REGENTS (US) | 2019-09-11 | — | — | EP | disclosed |
| US-9504688-B2 | Methods and compositions for treating bacterial infection | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-11-29 | — | — | US | disclosed |
| US-20150132352-A1 | METHODS AND COMPOSITIONS FOR TREATING BACTERIAL INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150132352-A1 | METHODS AND COMPOSITIONS FOR TREATING BACTERIAL INFECTION | MMP8, FPR1, ELANE | POLB 1692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.