Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24338980 | 0.82 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1 | |
| SCHEMBL17663674 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1MCHR1 | |
| SCHEMBL17664767 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL21154354 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1MCHR1 | |
| SCHEMBL18505841 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL13467249 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL17663676 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL18389109 | 0.79 | ALDH1A1 (0.57) | ALDH1A1TSHRTDP1 | |
| SCHEMBL12154838 | 0.78 | — | — | |
| SCHEMBL19003665 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2710063-B1 | PLASTICIZERS FOR POLYALKYLENE CABONATE RESIN COMPOSITIONS AND RESIN COMPOSITIONS INCLUDING THE SAME | SK INNOVATION CO LTD (KR) | 2017-07-12 | — | — | EP | disclosed |
| EP-2950380-B1 | ELECTROLYTE FOR LITHIUM AIR BATTERY AND LITHIUM AIR BATTERY INCLUDING THE SAME | SAMSUNG ELECTRONICS CO LTD (KR) | 2017-04-12 | — | — | EP | disclosed |
| US-20170001990-A1 | PIPERIDINE-DIONE DERIVATIVES | GENENTECH, INC. (US) | 2017-01-05 | — | — | US | disclosed |
| US-20160033520-A1 | FLUORESCENT COMPOUNDS | BIOTIUM, INC. | 2016-02-04 | — | — | US | disclosed |
| US-8834743-B2 | Dicarboxylate gemini surfactant that forms a lyotropic liquid crystal | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-8293276-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | BIND BIOSCIENCES, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-20120088848-A1 | METHODS AND COMPOSITIONS FOR CONTROLLED POLYPEPTIDE SYNTHESIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-04-12 | — | — | US | disclosed |
| US-20110274759-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | PFIZER INC. | 2011-11-10 | — | — | US | disclosed |
| US-20110172440-A1 | ROSIN DERIVED EPOXIDES AND CURING AGENTS | ZHANG JINWEN | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088848-A1 | METHODS AND COMPOSITIONS FOR CONTROLLED POLYPEPTIDE SYNTHESIS | NGLY1, LNPEP, NPPA | ALDH1A1 4856/4885TSHR 3552/4885TDP1 4645/4885 |
| US-20110274759-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | LDHA, LDHB, LPXN | ALDH1A1 410/4885TSHR 4622/4885TDP1 691/4885 |
| US-20170001990-A1 | PIPERIDINE-DIONE DERIVATIVES | DRD4, ADORA1, ADORA3 | ALDH1A1 132/4885TSHR 351/4885TDP1 515/4885 |
| US-20110172440-A1 | ROSIN DERIVED EPOXIDES AND CURING AGENTS | EPHX1, EPHX2, RCOR1 | ALDH1A1 70/4885TSHR 4818/4885TDP1 3299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.