Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455373 | 0.80 | MGLL (0.57) | MAPTKDM4EALDH1A1MEN1PKM | |
| SCHEMBL2091295 | 0.77 | MGLL (0.53) | MAPTALDH1A1PKMCYP1A2CA1 | |
| SCHEMBL2092147 | 0.76 | KDM4E (0.45) | MAPTKDM4EALDH1A1MEN1PKM | |
| SCHEMBL20201235 | 0.76 | KDM4E (0.45) | MAPTKDM4EALDH1A1MEN1PKM | |
| SCHEMBL5104129 | 0.76 | NQO1 (0.58) | MAPTKDM4EALDH1A1MEN1PKM | |
| SCHEMBL7013183 | 0.74 | LTA4H (0.55) | KDM4EMEN1PKMKMT2ACA1 | |
| SCHEMBL11417007 | 0.74 | CYP1A2 (1.00) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL1670288 | 0.74 | CYP1A2 (0.52) | MAPTKDM4EALDH1A1MEN1PKM | |
| SCHEMBL16720130 | 0.73 | CHRNB2 (0.49) | CYP1A2CYP2C9 | |
| SCHEMBL4722619 | 0.73 | CYP1A2 (0.54) | MAPTKDM4EALDH1A1MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141220-A | Aza-BODIPY compound and application thereof in-vivo tracing of nanoparticles | 复旦大学 | 2022-10-04 | — | — | CN | claimed |
| US-10591435-B2 | Electropolymerization onto flexible substrates for electronic applications | CORNELL UNIVERSITY (US) | 2020-03-17 | — | — | US | claimed |
| CN-107434830-A | Wide-distribution polypropylene catalyst component, preparation method and catalyst thereof | 中国石油天然气股份有限公司 | 2017-12-05 | — | — | CN | claimed |
| US-20170023513-A1 | ELECTROPOLYMERIZATION ONTO FLEXIBLE SUBSTRATES FOR ELECTRONIC APPLICATIONS | CORNELL UNIVERSITY | 2017-01-26 | — | — | US | claimed |
| CN-117377668-A | Inhalant formulations of PGDH inhibitors and methods of use thereof | 迈欧伏特治疗公司 | 2024-01-09 | — | — | CN | disclosed |
| US-20230167067-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2023-06-01 | — | — | US | disclosed |
| CN-115335043-A | PGDH inhibitors and methods of making and using | 迈欧伏特治疗公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-115141220-A | Aza-BODIPY compound and application thereof in-vivo tracing of nanoparticles | 复旦大学 | 2022-10-04 | — | — | CN | disclosed |
| CN-109456205-B | N-arylation method in aqueous phase system by using substituted quinoline or isoquinoline hydrazide pyridine-N-oxide as ligand | 石河子大学 | 2021-09-21 | — | — | CN | disclosed |
| EP-3326715-B1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | CE PHARM CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |
| EP-3326715-B1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | CE PHARM CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |
| CN-106362797-B | Oxalic acid amide ligand and application thereof in copper-catalyzed aryl halide coupling reaction | 浙江中科创越药业有限公司 | 2021-05-28 | — | — | CN | disclosed |
| EP-1874780-A1 | 4-PIPERAZINYLTHIENO[2,3-D]PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | Pharmacia & Upjohn Company LLC (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2007013673-A1 | FUSED HETEROCYCLES AS LCK INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2007-02-01 | — | — | WO | disclosed |
| WO-2006100591-A1 | 4-PIPERAZINNYLTHIENO [2,3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |
| CN-1229330-C | N-arylating method using amino-acid as additives | SHANGHAI INST ORGANIC CHEM (CN) | 2005-11-30 | — | — | CN | disclosed |
| US-6911468-B2 | Tyrosine phosphatase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-06-28 | — | — | US | disclosed |
| CN-1450049-A | N-arylating method using amino-acid as additives | SHANGHAI INST ORGANIC CHEM (CN) | 2003-10-22 | — | — | CN | disclosed |
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1284260-A1 | TYROSINE PHOSPHATASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | PTPRC, PTPN1, PTPRM | MAPT 4800/4885KDM4E 171/4885ALDH1A1 2470/4885 |
| US-20230167067-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | PPOX, AOC2, AOC3 | MAPT 3005/4885KDM4E 766/4885ALDH1A1 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.