Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1671504 | 0.73 | ERN1 (0.36) | ERN1AMY1APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL20924977 | 0.61 | ERN1 (0.43) | ERN1AMY1APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL19214428 | 0.60 | ALDH1A1 (0.55) | ERN1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL10340365 | 0.60 | AMY1A (0.50) | ERN1AMY1APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL16852397 | 0.59 | AMY1A (0.51) | ERN1AMY1APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL17508246 | 0.58 | ERN1 (0.57) | ERN1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1682483 | 0.58 | ERN1 (0.42) | ERN1AMY1AGRM2ALDH1A1 | |
| SCHEMBL245504 | 0.57 | ALDH1A1 (0.63) | ERN1AMY1AALDH1A1 | |
| SCHEMBL1528920 | 0.56 | CD274 (0.48) | ERN1AMY1APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL8471545 | 0.56 | PDGFRB (0.37) | ERN1AMY1AALDH1A1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |