SCHEMBL245504

SCHEMBL245504

COc1ccc(C=O)c(F)c1

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.63
TRIM24 O15164 1/20 0.61
TYR P14679 1/20 0.61
TRIM33 Q9UPN9 1/20 0.61
CYP1A2 P05177 4/20 0.59
CYP1A1 P04798 2/20 0.59
CYP1B1 Q16678 2/20 0.59
ERN1 O75460 3/20 0.56
AMY1A P0DUB6 1/20 0.51
CYP2C19 P33261 2/20 0.49
KDM4E B2RXH2 1/20 0.49
MAPT P10636 1/20 0.49
CYP2A6 P11509 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.45
LMNA P02545 1/20 0.44
CYP2C9 P11712 1/20 0.44
CPS1 P31327 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28823895 0.98 ALDH1A1 (0.61) ALDH1A1TRIM24TYRTRIM33CYP1A2
SCHEMBL756641 0.89 ALDH1A1 (0.51) ALDH1A1TRIM24TYRTRIM33CYP1A2
SCHEMBL1125382 0.85 ERN1 (0.53) ALDH1A1TRIM24TYRTRIM33CYP1A2
SCHEMBL387186 0.84 ERN1 (0.61) ALDH1A1TRIM24TYRTRIM33CYP1A2
SCHEMBL18144085 0.83 NFE2L2 (0.56) ALDH1A1CYP1A2CYP1A1CYP1B1KDM4E
SCHEMBL18144089 0.83 NFE2L2 (0.56) ALDH1A1CYP1A2CYP1A1CYP1B1KDM4E
SCHEMBL21402611 0.82 CYP1A2 (0.61) ALDH1A1TRIM24TYRTRIM33CYP1A2
SCHEMBL3321045 0.82 CYP1A1 (0.61) ALDH1A1TRIM24TYRTRIM33CYP1A2
SCHEMBL19499354 0.81 ALDH1A1 (0.47) ALDH1A1TRIM24TYRTRIM33CYP1A2
SCHEMBL505306 0.81 ERN1 (0.56) ALDH1A1TRIM24TYRTRIM33CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120117949-A Method for directly preparing tertiary amine compound from aromatic aldehyde, ketone and secondary amine 湖南大学 2025-06-10 CN claimed
CN-119841727-A Method for directly preparing carboxylic ester compound from aromatic aldehyde, ketone and carboxylic acid 湖南第一师范学院 2025-04-18 CN claimed
CN-119119116-A Rhein phosphoryl derivative and synthetic method and application thereof 甘肃中医药大学 2024-12-13 CN claimed
CN-113164459-B Monoacylglycerol lipase modulators 詹森药业有限公司 2024-09-03 CN claimed
CN-117820095-A Process method for synthesizing 2-fluoro-4-hydroxybenzaldehyde 大连双硼医药化工有限公司 2024-04-05 CN claimed
CN-114981247-A Piperazine compounds for inhibiting CPS1 卫材R&D管理有限公司 2022-08-30 CN claimed
CN-111848527-A 4-chloro-2- (2-fluoro-4-methoxyphenyl) -6-methoxyquinazoline and synthetic method thereof 南通大学 2020-10-30 CN claimed
CN-106810496-B A kind of 8-hydroxyquinoline nickel complex and preparation method thereof 广东工业大学 2018-10-19 CN claimed
CN-104649879-B Substituted benzene methylene 1,2,3,4-Tetrahydrooxonaphthalene analog derivative and preparation method, application 中国人民解放军第二军医大学 2017-01-04 CN claimed
CN-104649879-A Substituted benzylidene tetralone derivatives and preparation method and applications UNIV PLA 2ND MILITARY MEDICAL 2015-05-27 CN claimed
CN-104388080-A Yellow-light electroluminescent material based on 8-hydroxyquinoline zinc metal complex tripolymer and controllable preparation method thereof UNIV GUANGDONG TECHNOLOGY 2015-03-04 CN claimed
CN-1589136-A Pharmaceutical and cosmetic compositions containing aromatic aldehydes bearing oxygen-containing groups CUTANIX CORP (US) 2005-03-02 CN claimed
US-20030124157-A1 Compositions containing aromatic aldehydes and their use in treatments ALLERGAN, INC. 2003-07-03 US claimed
EP-4727540-A2 FUSED BICYCLIC HETEROCYCLIC OR HETERO ARYL AMIDE COMPOUNDS Quantx Biosciences US, Inc. (US) 2026-04-22 EP disclosed
US-12577243-B2 Monoacylglycerol lipase modulators JANSSEN PHARMACEUTICA NV (BE) 2026-03-17 US disclosed
EP-4696691-A1 TRICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Huilun Pharmaceutical Co., Ltd. (CN) 2026-02-18 EP disclosed
US-4730068-A SPECIAL EFFECT ON BREAST CANCER ASTA-WERKE AKTIENGESELLSCHAFT (DE) 1988-03-08 US disclosed
CN-87105734-A The dopamine-inhibitor 1988-02-24 CN disclosed
CN-86100815-A The preparation method who suppresses (1, the 2-diphenyl ethylene diamine)-platinum (II) complex compound of tumour 1986-11-26 CN disclosed
EP-0193055-A1 Antitumorals(1,2-diphenyl-ethylene diamine)-platinum (II) complexes ASTA Pharma AG (DE) 1986-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577243-B2 Monoacylglycerol lipase modulators MGLL, LPL, FAAH ALDH1A1 587/4885TRIM24 4302/4885TYR 792/4885
US-20030124157-A1 Compositions containing aromatic aldehydes and their use in treatments TYR, ALDH2, AOX1 ALDH1A1 4/4885TRIM24 3539/4885TYR 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.