Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12800387 | 0.78 | MAPT (0.53) | MAPTKMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL22283897 | 0.78 | ADORA1 (0.51) | ADORA1MAPTPTPN1PRKAB2PRKAG1 | |
| SCHEMBL1185412 | 0.78 | ALDH1A1 (0.51) | ADORA1MAPTPTPN1PRKAB2PRKAG1 | |
| SCHEMBL7689092 | 0.70 | POLB (0.49) | ADORA1MAPTPTPN1MEN1KMT2A | |
| SCHEMBL12670739 | 0.69 | PRKAB2 (0.51) | ADORA1MAPTPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL140629 | 0.69 | PGR (0.49) | ADORA1MAPTPTPN1PRKAB2PRKAG1 | |
| SCHEMBL11021063 | 0.69 | PIM1 (0.49) | MAPTPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL21608938 | 0.69 | ALDH1A1 (0.54) | ADORA1MAPTPTPN1MEN1KMT2A | |
| SCHEMBL7574828 | 0.69 | KMT2A (0.55) | ADORA1MAPTPTPN1MEN1KMT2A | |
| SCHEMBL1670787 | 0.68 | MAPKAPK2 (0.47) | ADORA1MAPTPTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |