Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 3/20 | 0.42 |
| ▸ | METAP2 | P50579 | 2/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720887 | 0.89 | METAP1 (0.42) | METAP1METAP2TDP2KMT2A | |
| SCHEMBL16719483 | 0.74 | KMT2A (0.44) | KMT2A | |
| SCHEMBL16720665 | 0.71 | CDC7 (0.32) | METAP1METAP2 | |
| SCHEMBL16720616 | 0.70 | METAP2 (0.37) | METAP1METAP2TDP2 | |
| SCHEMBL16719747 | 0.70 | KMT2A (0.64) | KMT2A | |
| SCHEMBL16720261 | 0.68 | CASP6 (0.35) | METAP1METAP2 | |
| SCHEMBL16719353 | 0.68 | METAP2 (0.40) | METAP1METAP2TDP2 | |
| SCHEMBL16720695 | 0.67 | KDM4A (0.34) | METAP1METAP2 | |
| SCHEMBL1419488 | 0.67 | MEN1 (0.37) | KMT2A | |
| SCHEMBL16720684 | 0.66 | NPC1 (0.37) | METAP1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |