Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM4B | O94953 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719446 | 0.68 | METAP2 (0.33) | KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL14994553 | 0.67 | METAP1 (0.33) | KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL7964249 | 0.66 | TSHR (0.50) | KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL16719690 | 0.65 | METAP1 (0.45) | — | |
| SCHEMBL16720559 | 0.64 | MMP3 (0.38) | — | |
| SCHEMBL16720557 | 0.63 | KDM4A (0.37) | KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL496710 | 0.63 | LTA4H (0.47) | KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL16720484 | 0.62 | POLB (0.45) | KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL16720219 | 0.61 | KDM4A (0.37) | KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL16719511 | 0.61 | HSD17B1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |