Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284646 | 0.81 | GPR84 (0.34) | TSHRHPGDALDH1A1HCAR2ATM | |
| SCHEMBL10933728 | 0.79 | CA2 (0.36) | HPGDALDH1A1HCAR2ATMCA2 | |
| SCHEMBL18007391 | 0.76 | GPR84 (0.31) | ALDH1A1 | |
| SCHEMBL17821128 | 0.76 | GPR84 (0.31) | ALDH1A1 | |
| SCHEMBL29061780 | 0.73 | GPR84 (0.37) | HPGDHCAR2 | |
| SCHEMBL29061782 | 0.73 | GPR84 (0.37) | HPGDHCAR2 | |
| SCHEMBL9753360 | 0.73 | GPR84 (0.37) | HPGDHCAR2 | |
| SCHEMBL8595353 | 0.73 | CES2 (0.38) | TSHRHPGDALDH1A1TP53HCAR2 | |
| SCHEMBL690601 | 0.73 | HSPD1 (0.46) | HPGDCA2MAPK1 | |
| SCHEMBL3284825 | 0.72 | ALDH1A1 (0.40) | TSHRHPGDALDH1A1TP53HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068831-B1 | ACCELERATOR COMPOSITIONS AND METHODS | ROBINSON BROS LTD (GB) | 2019-06-19 | — | — | EP | disclosed |
| US-10000623-B2 | Accelerator compositions and methods | ROBINSON BROTHERS LIMITED (GB) | 2018-06-19 | — | — | US | disclosed |
| EP-3068831-A1 | ACCELERATOR COMPOSITIONS AND METHODS | ROBINSON BROTHERS LIMITED (GB) | 2016-09-21 | — | — | EP | disclosed |
| US-20160264760-A1 | ACCELERATOR COMPOSITIONS AND METHODS | ROBINSON BROTHERS LIMITED (GB) | 2016-09-15 | — | — | US | disclosed |
| WO-2015071641-A1 | ACCELERATOR COMPOSITIONS AND METHODS | ROBINSON BROTHERS LIMITED (GB) | 2015-05-21 | — | — | WO | disclosed |