SCHEMBL284646

SCHEMBL284646

CCCCOC(CCCC)(C(=O)O)C(O)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.34
FFAR1 O14842 1/20 0.34
ALDH1A1 P00352 1/20 0.33
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
ATM Q13315 1/20 0.32
CA2 P00918 1/20 0.32
MAPK1 P28482 1/20 0.32
CPT2 P23786 1/20 0.31
ACLY P53396 1/20 0.31
HPGD P15428 2/20 0.31
MEN1 O00255 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HSPD1 P10809 1/20 0.30
BLM P54132 1/20 0.30
HSPE1 P61604 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9753360 0.92 GPR84 (0.37) GPR84FFAR1HCAR2HPGDMEN1
SCHEMBL29061782 0.92 GPR84 (0.37) GPR84FFAR1HCAR2HPGDMEN1
SCHEMBL29061780 0.92 GPR84 (0.37) GPR84FFAR1HCAR2HPGDMEN1
SCHEMBL8935620 0.90 GPR84 (0.40) GPR84FFAR1HCAR2HPGDMEN1
SCHEMBL455822 0.90 GPR84 (0.40) GPR84FFAR1HCAR2HPGDMEN1
SCHEMBL17373019 0.83 TERT (0.42) PPARGPPARAATMACLYRECQL
SCHEMBL3615672 0.83 CPT2 (0.32) PPARGPPARACPT2ACLY
SCHEMBL17821128 0.81 GPR84 (0.31) GPR84FFAR1ALDH1A1
SCHEMBL18007391 0.81 GPR84 (0.31) GPR84FFAR1ALDH1A1
SCHEMBL10933728 0.81 CA2 (0.36) GPR84FFAR1ALDH1A1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 588 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9149439-B2 Multi-particulate, modified-release composition SANDOZ AG (CH) 2015-10-06 US claimed
WO-2014029953-A1 HOT MELT EXTRUDED (HME) PHARMACEUTICAL COMPOSITION OF CINACALCET CIPLA LIMITED (IN) 2014-02-27 WO claimed
US-8168228-B2 Oral micropellets containing an antibiotic having an inner coating of a cellulose polymer (not enteric)and an outer coating of an enteric coating polymer; particle size of 100 to 650 mu m.; lack of bitter taste; fast dissolution; increased antibiotic bioavailability compared pellets having a matrix SANDOZ AG (CH) 2012-05-01 US claimed
US-20100179210-A1 NOVEL ENANTIOMERICALLY PURE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS Piramal Enterprises Limited (IN) 2010-07-15 US claimed
US-20100173921-A1 Antiretroviral Solid Oral Composition CIPLA LIMITED (IN) 2010-07-08 US claimed
EP-2046738-A1 ENANTIOMERICALLY PURE FLAVONE DERIVATIVES FOR THE TREATMENT OF POLIFERATIVE DISORDERS AND PROCESSES FOR THEIR PREPARATION Piramal Life Sciences Limited (IN) 2009-04-15 EP claimed
EP-1680088-B1 Taste-masked formulation comprising clarithromycin SANDOZ AG (CH) 2008-12-03 EP claimed
WO-2008017867-A2 ANTIRETROVIRAL SOLID ORAL COMPOSITION WITH AT LEAST ONE WATER INSOLUBLE POLYMER CIPLA LIMITED (IN) 2008-02-14 WO claimed
WO-2007148158-A1 ENANTIOMERICALLY PURE FLAVONE DERIVATIVES FOR THE TREATMENT OF POLIFERATIVE DISORDERS AND PROCESSES FOR THEIR PREPARATION PIRAMAL LIFE SCIENCES LIMITED (IN) 2007-12-27 WO claimed
US-20070134344-A1 Antibiotic compositions SANDOZ AG (CH) 2007-06-14 US claimed
US-20070048379-A1 Valproate tablet GUO MINTONG 2007-03-01 US claimed
WO-2006102446-A2 MULTI-PARTICULATE, MODIFIED-RELEASED COLONIC COMPOSITION SANDOZ AG (CH) 2006-09-28 WO claimed
US-20060210631-A1 Multi-particulate, modified-release composition SANDOZ AG (CH) 2006-09-21 US claimed
EP-1680088-A1 ANTIBIOTIC COMPOSITIONS Sandoz AG (CH) 2006-07-19 EP claimed
US-20050181052-A1 Lansoprazole microtablets PATEL SATISHKUMAR A (US) 2005-08-18 US claimed
WO-2005039536-A1 ANTIBIOTIC COMPOSITIONS SANDOZ AG (CH) 2005-05-06 WO claimed
US-20050084541-A1 Antibiotic compositions SANDOZ, AG (CH) 2005-04-21 US claimed
EP-0951905-A2 Pharmaceutical compositions for programmed therapeutical coverage APR APPLIED PHARMA RESEARCH S.A. (CH) 1999-10-27 EP claimed
EP-4081215-B1 METHODS AND COMPOSITIONS FOR INHIBITION OF DIHYDROOROTATE DEHYDROGENASE OHIO STATE INNOVATION FOUNDATION (US) 2026-05-20 EP disclosed
US-4743673-A MEDICAL EQUIPMENT, DRUG DELIVERY, ANTIFRICTION TYNDALE PLAINS-HUNTER, LTD. (US) 1988-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100179210-A1 NOVEL ENANTIOMERICALLY PURE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS CDK2, CDK9, CDK1 GPR84 2070/4885FFAR1 1925/4885ALDH1A1 1497/4885
US-20070048379-A1 Valproate tablet CACNA1A, SUCLG2, CACNA1G GPR84 3013/4885FFAR1 2026/4885ALDH1A1 1386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.