Sugi Predict

Sugi Predict / Compounds / SCHEMBL167279

SCHEMBL167279

SCHEMBL167279

CC(=O)Oc1ccc(S)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 0.64
▸ MAPT P10636 3/20 0.57
▸ POLB P06746 1/20 0.57
▸ PKM P14618 1/20 0.57
▸ ELANE P08246 2/20 0.55
▸ HSD17B10 Q99714 1/20 0.53
▸ GAA P10253 2/20 0.52
▸ ALDH1A1 P00352 1/20 0.52
▸ HSP90AA1 P07900 1/20 0.52
▸ KDM4E B2RXH2 3/20 0.50
▸ CYP3A4 P08684 3/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ TTR P02766 1/20 0.50
▸ TP53 P04637 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ GLA P06280 1/20 0.48
▸ ESR1 P03372 2/20 0.47
▸ SLC6A3 Q01959 2/20 0.47
▸ PGR P06401 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL269329 0.87 LMNA (0.80) LMNAMAPTPOLBPKMELANE
SCHEMBL14760365 0.85 LMNA (0.76) LMNAMAPTPOLBPKMELANE
Lithium SCHEMBL30522746 0.85 LMNA (0.76) LMNAMAPTPOLBPKMELANE
SCHEMBL11229844 0.83 LMNA (0.43) LMNAMAPTPOLBPKMELANE
SCHEMBL21019611 0.81 CA12 (0.54) LMNAMAPTPOLBGAAALDH1A1
SCHEMBL11419351 0.81 LMNA (0.64) LMNAMAPTPOLBPKMELANE
SCHEMBL24435576 0.80 LMNA (0.70) LMNAMAPTPOLBPKMELANE
SCHEMBL6667339 0.80 LMNA (0.70) LMNAMAPTPOLBPKMELANE
SCHEMBL9158246 0.80 HSD17B10 (0.76) LMNAMAPTPOLBPKMELANE
SCHEMBL9325116 0.80 LMNA (0.70) LMNAMAPTPOLBPKMELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600746-B2 Synthetic methods using native chemical ligation in flow THE UNIVERSITY OF SYDNEY (AU) 2026-04-14 — — US claimed
CN-116874464-A Polymerizable single-component photoinitiator and preparation method thereof 江苏集萃光敏电子材料研究所有限公司 2023-10-13 — — CN claimed
US-20230133885-A1 NEW SYNTHETIC METHODS USING NATIVE CHEMICAL LIGATION IN FLOW THE UNIVERSITY OF SYDNEY (AU) 2023-05-04 — — US claimed
CN-112457417-B Method for preparing scorpion toxin polypeptide 合肥科生景肽生物科技有限公司 2022-08-30 — — CN claimed
CN-114487383-A Trimeric ubiquitin chain probe and synthetic method and application thereof 合肥科生景肽生物科技有限公司 2022-05-13 — — CN claimed
EP-3797115-A1 NEW SYNTHETIC METHODS USING NATIVE CHEMICAL LIGATION IN FLOW The University Of Sydney (AU) 2021-03-31 — — EP claimed
CN-112457417-A Method for preparing scorpion toxin polypeptide 合肥科生景肽生物科技有限公司 2021-03-09 — — CN claimed
CN-108164748-B A kind of rubber bonding agent and its preparation and application 同济大学 2019-12-03 — — CN claimed
WO-2019222805-A1 NEW SYNTHETIC METHODS USING NATIVE CHEMICAL LIGATION IN FLOW THE UNIVERSITY OF SYDNEY (AU) 2019-11-28 — — WO claimed
CN-110229333-A A kind of synthetic method of new type polyimide 湘潭大学 2019-09-13 — — CN claimed
CN-106410270-B It is a kind of using carbon dioxide-base polycarbonate as lithium single-ion conductor solid polymer electrolyte of main chain and preparation method thereof 中山大学 2018-12-21 — — CN claimed
CN-108164748-A A kind of rubber bonding agent and its preparation and application 同济大学 2018-06-15 — — CN claimed
CN-108138204-A Method for producing thioester using sortase A 豪夫迈·罗氏有限公司 2018-06-08 — — CN claimed
CN-108059688-A A kind of nanometer additive and its preparation and application 同济大学 2018-05-22 — — CN claimed
CN-106410270-A Single-lithium-ion-conducting solid polymer electrolyte adopting carbon dioxide based polycarbonate as main chain and preparation method of single-lithium-ion-conducting solid polymer electrolyte 中山大学 2017-02-15 — — CN claimed
CN-103910886-B Application in the conjugates of hyaluronic acid of halfcystine functionalization and synthetic method thereof and the hydrogel that formed at Injectable in-situ HAINAN UNIVERSITY (CN) 2016-04-06 — — CN claimed
US-7674881-B2 Convergent synthesis of proteins by kinetically controlled ligation THE UNIVERSITY OF CHICAGO (US) 2010-03-09 — — US claimed
WO-2007100358-A2 CONVERGENT SYNTHESIS OF PROTEINS BY KINETICALLY CONTROLLED LIGATION UNIVERSITY OF CHICAGO (US) 2007-09-07 — — WO claimed
US-20070082378-A1 Convergent synthesis of proteins by kinetically controlled ligation UNIVERSITY OF CHICAGO (US) 2007-04-12 — — US claimed
US-4826888-A STORAGE STABLE, DISCOLORATION INHIBITION MITSUBISHI RAYON CO., LTD. (JP) 1989-05-02 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070082378-A1 Convergent synthesis of proteins by kinetically controlled ligation NPEPPS, PTMS, QPCTL LMNA 4126/4885MAPT 2728/4885POLB 2006/4885
US-12600746-B2 Synthetic methods using native chemical ligation in flow SCLY, CTH, CBS LMNA 4108/4885MAPT 4429/4885POLB 1266/4885
US-20230133885-A1 NEW SYNTHETIC METHODS USING NATIVE CHEMICAL LIGATION IN FLOW SCLY, SRM, SELENOI LMNA 4355/4885MAPT 4424/4885POLB 2325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.