Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 5/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15540233 | 1.00 | ABCB1 (0.71) | ABCB1POLBKMT2AMEN1SGMS2 | |
| SCHEMBL15540629 | 1.00 | ABCB1 (0.71) | ABCB1POLBKMT2AMEN1SGMS2 | |
| SCHEMBL16730153 | 1.00 | ABCB1 (0.71) | ABCB1POLBKMT2AMEN1SGMS2 | |
| SCHEMBL16730223 | 0.82 | HTR1A (0.52) | ABCB1POLBKMT2ASGMS2ALDH1A1 | |
| SCHEMBL15539841 | 0.82 | HTR1A (0.52) | ABCB1POLBKMT2ASGMS2ALDH1A1 | |
| SCHEMBL22639942 | 0.81 | POLB (0.98) | ABCB1POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL22639704 | 0.81 | POLB (0.98) | ABCB1POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL15539199 | 0.78 | SGMS2 (0.50) | ABCB1POLBKMT2AMEN1SGMS2 | |
| SCHEMBL15539163 | 0.78 | FAAH (0.58) | ABCB1POLBKMT2AMEN1SGMS2 | |
| SCHEMBL16730206 | 0.78 | FAAH (0.58) | ABCB1POLBKMT2AMEN1SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318887-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2016-11-03 | — | — | US | disclosed |
| US-20150141437-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSTÄT WIEN (AT) | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318887-A1 | AMIDOPHENOXYPROPANOLAMINES | ADH5, HRH3, PNMT | ABCB1 1296/4885POLB 3154/4885KMT2A 3168/4885 |
| US-20150141437-A1 | AMIDOPHENOXYPROPANOLAMINES | ADH5, HRH3, PNMT | ABCB1 1296/4885POLB 3154/4885KMT2A 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.