Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735624 | 0.90 | CNR1 (0.43) | RXFP1CNR1CNR2POLBHSP90AA1 | |
| SCHEMBL16735620 | 0.80 | KCNH2 (0.45) | RXFP1POLBHSP90AA1HSP90AB1LMNA | |
| SCHEMBL16735639 | 0.75 | RXFP1 (0.46) | RXFP1POLBHSP90AA1LMNACHRNA7 | |
| SCHEMBL16735662 | 0.74 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1LMNAALDH1A1 | |
| SCHEMBL16735578 | 0.73 | POLB (0.56) | RXFP1POLBMAPTHSP90AA1LMNA | |
| SCHEMBL4930657 | 0.72 | POLB (0.44) | RXFP1CNR1CNR2POLBCHRNA7 | |
| SCHEMBL4930664 | 0.72 | POLB (0.44) | RXFP1CNR1CNR2POLBCHRNA7 | |
| SCHEMBL16735670 | 0.72 | MAPT (0.55) | RXFP1POLBMAPTHTTLMNA | |
| SCHEMBL16735647 | 0.71 | POLB (0.49) | RXFP1POLBMAPTHSP90AA1LMNA | |
| SCHEMBL16735634 | 0.71 | KDM4C (0.54) | RXFP1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-B1 | TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM SA (LU) | 2015-05-27 | — | — | EP | claimed |