Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735587 | 0.90 | RXFP1 (0.38) | CNR1CNR2RXFP1POLBHSP90AA1 | |
| SCHEMBL16735620 | 0.85 | KCNH2 (0.45) | RXFP1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16735639 | 0.82 | RXFP1 (0.46) | RXFP1POLBHSP90AA1HTR3A | |
| SCHEMBL16735662 | 0.81 | HSP90AA1 (0.57) | HSD11B1HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL2143834 | 0.78 | ALDH1A1 (0.51) | RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16735578 | 0.78 | POLB (0.56) | RXFP1POLBSMN1; SMN2HSP90AA1ALDH1A1 | |
| SCHEMBL4930657 | 0.77 | POLB (0.44) | CNR1CNR2RXFP1POLBHTR3A | |
| SCHEMBL4930664 | 0.77 | POLB (0.44) | CNR1CNR2RXFP1POLBHTR3A | |
| SCHEMBL16735670 | 0.76 | MAPT (0.55) | RXFP1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16735667 | 0.75 | POLB (0.51) | RXFP1POLBRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-B1 | TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM SA (LU) | 2015-05-27 | — | — | EP | claimed |