Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735578 | 0.83 | POLB (0.56) | RXFP1POLBDPP4DPP8HSP90AA1 | |
| SCHEMBL16735624 | 0.82 | CNR1 (0.43) | RXFP1POLBHSP90AA1HTR3A | |
| SCHEMBL16735670 | 0.81 | MAPT (0.55) | RXFP1POLBLMNA | |
| SCHEMBL16735634 | 0.81 | KDM4C (0.54) | RXFP1POLB | |
| SCHEMBL16735667 | 0.81 | POLB (0.51) | RXFP1POLB | |
| SCHEMBL16735647 | 0.79 | POLB (0.49) | RXFP1POLBHSP90AA1LMNA | |
| SCHEMBL16735593 | 0.79 | RXFP1 (0.56) | RXFP1POLBHCRTR1HCRTR2 | |
| SCHEMBL16735636 | 0.79 | HSP90AA1 (0.62) | POLBHSP90AA1 | |
| SCHEMBL16735663 | 0.78 | RXFP1 (0.45) | RXFP1POLBHCRTR1HCRTR2LMNA | |
| SCHEMBL16735605 | 0.78 | POLB (0.51) | RXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-B1 | TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM SA (LU) | 2015-05-27 | — | — | EP | claimed |