Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735624 | 0.85 | CNR1 (0.43) | RXFP1POLBNPC1ALDH1A1RAB9A | |
| SCHEMBL16735680 | 0.83 | POLB (0.42) | KCNH2HRH3HPGDMEN1KMT2A | |
| SCHEMBL16735670 | 0.82 | MAPT (0.55) | HPGDKDM4EMEN1KMT2AGAA | |
| SCHEMBL16735667 | 0.81 | POLB (0.51) | HPGDKDM4ETSHRKMT2ARXFP1 | |
| SCHEMBL24026149 | 0.81 | GAA (0.55) | HRH3HPGDMEN1KMT2AGAA | |
| SCHEMBL16735662 | 0.80 | HSP90AA1 (0.57) | KDM4EMEN1KMT2AALDH1A1HSP90AA1 | |
| SCHEMBL16735587 | 0.80 | RXFP1 (0.38) | RXFP1POLBALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL16735578 | 0.79 | POLB (0.56) | HPGDKDM4EGAARXFP1POLB | |
| SCHEMBL4930657 | 0.78 | POLB (0.44) | RXFP1POLB | |
| SCHEMBL4930664 | 0.78 | POLB (0.44) | RXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-B1 | TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM SA (LU) | 2015-05-27 | — | — | EP | claimed |