Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | OXTR | P30559 | 7/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2143866 | 0.83 | BCHE (0.47) | MEN1KMT2AOXTRAVPR1AMAPT | |
| SCHEMBL16735603 | 0.76 | TSHR (0.44) | MAPTALDH1A1KDM4E | |
| SCHEMBL12443455 | 0.68 | PDE4A (0.47) | KMT2AOXTRAVPR1AALDH1A1PDE4A | |
| SCHEMBL16735591 | 0.67 | HSD11B1 (0.53) | RAB9ANPC1POLB | |
| SCHEMBL16735622 | 0.66 | POLB (0.53) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL13612605 | 0.66 | PDE4A (0.45) | KMT2AOXTRAVPR1AMAPTALDH1A1 | |
| SCHEMBL15659780 | 0.66 | PSMD14 (0.49) | MEN1KMT2ANPC1OXTRAVPR1A | |
| SCHEMBL6358384 | 0.66 | L3MBTL1 (0.45) | MEN1KMT2ARAB9ANPC1OXTR | |
| SCHEMBL13605180 | 0.65 | PDE4A (0.44) | OXTRAVPR1AALDH1A1PDE4APDE4B | |
| SCHEMBL16735660 | 0.65 | L3MBTL1 (0.54) | MEN1KMT2AALDH1A1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-B1 | TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM SA (LU) | 2015-05-27 | — | — | EP | claimed |