Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705933 | 0.73 | P2RX4 (0.57) | P2RX4ALDH1A1HPGDRAB9ACYP1A2 | |
| SCHEMBL25419666 | 0.71 | ALDH1A1 (0.36) | P2RX4ALDH1A1HPGDRAB9ACYP1A2 | |
| SCHEMBL15413770 | 0.71 | P2RX4 (0.40) | P2RX4ALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL23178104 | 0.69 | P2RX4 (0.40) | P2RX4ALDH1A1HPGDRAB9ACYP1A2 | |
| SCHEMBL31587978 | 0.68 | P2RX4 (0.38) | P2RX4ALDH1A1HPGDCYP1A2MAPT | |
| SCHEMBL3859175 | 0.68 | LMNA (0.58) | P2RX4ALDH1A1RAB9ACYP2C19CYP3A4 | |
| SCHEMBL275516 | 0.66 | SLC6A4 (0.40) | P2RX4ALDH1A1MAPTKDM4EGLA | |
| SCHEMBL23496994 | 0.64 | P2RX4 (0.45) | P2RX4ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL16486276 | 0.63 | KDM4E (0.46) | ALDH1A1HPGDRAB9ACYP1A2CYP2C19 | |
| SCHEMBL12776605 | 0.61 | P2RX4 (0.49) | P2RX4ALDH1A1HPGDRAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10933169-B2 | Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto | EMORY UNIVERSITY (US) | 2021-03-02 | — | — | US | disclosed |
| US-10434220-B2 | Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto | EMORY UNIVERSITY (US) | 2019-10-08 | — | — | US | disclosed |
| US-20160089478-A1 | BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO | UNIV EMORY (US) | 2016-03-31 | — | — | US | disclosed |
| US-20150148292-A1 | BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO | UNIV EMORY (US) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148292-A1 | BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO | BMP4, BMP2, BMP1 | P2RX4 3107/4885ALDH1A1 3881/4885HPGD 2253/4885 |
| US-10434220-B2 | Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto | BMP2, BMP4, BMP1 | P2RX4 2974/4885ALDH1A1 1840/4885HPGD 2378/4885 |
| US-10933169-B2 | Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto | BMP2, BMP4, BMP1 | P2RX4 2974/4885ALDH1A1 1840/4885HPGD 2378/4885 |
| US-20160089478-A1 | BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO | BMP2, BMP4, BMP1 | P2RX4 2974/4885ALDH1A1 1840/4885HPGD 2378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.