Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.53 |
| ▸ | NAMPT | P43490 | 5/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22040078 | 0.88 | TRPV1 (0.54) | TRPV1NAMPTPRSS1CTSGCTRB1 | |
| SCHEMBL2590735 | 0.81 | TRPV1 (0.50) | TRPV1NAMPTMAPK14 | |
| SCHEMBL12301890 | 0.81 | NPC1 (0.57) | NAMPTCYP2C9MAPK14 | |
| SCHEMBL20788451 | 0.79 | OGG1 (0.53) | NAMPTPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL18698021 | 0.79 | TRPV1 (0.46) | TRPV1NAMPTPRSS1CTSGCTRB1 | |
| SCHEMBL21590340 | 0.79 | PRSS1 (0.65) | NAMPTPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL387816 | 0.79 | TRPV1 (0.54) | TRPV1 | |
| SCHEMBL25231901 | 0.78 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL4688446 | 0.77 | DGAT1 (0.47) | TRPV1 | |
| SCHEMBL18652074 | 0.77 | TRPV1 (0.44) | TRPV1NAMPTPRSS1CTSGCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074375-B1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | BOEHRINGER INGELHEIM INT (DE) | 2018-04-04 | — | — | EP | disclosed |
| EP-3074375-B1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | BOEHRINGER INGELHEIM INT (DE) | 2018-04-04 | — | — | EP | disclosed |
| EP-3074375-A1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | Boehringer Ingelheim International GmbH (DE) | 2016-10-05 | — | — | EP | disclosed |
| US-9308194-B2 | Indanyloxyphenylcyclopropanecarboxylic acids | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-12 | — | — | US | disclosed |
| US-9308194-B2 | Indanyloxyphenylcyclopropanecarboxylic acids | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-12 | — | — | US | disclosed |
| US-9308194-B2 | Indanyloxyphenylcyclopropanecarboxylic acids | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-12 | — | — | US | disclosed |
| WO-2015078802-A1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-06-04 | — | — | WO | disclosed |
| WO-2015078802-A1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-06-04 | — | — | WO | disclosed |
| US-20150148347-A1 | INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-05-28 | — | — | US | disclosed |
| US-20150148347-A1 | INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-05-28 | — | — | US | disclosed |
| US-20150148347-A1 | INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148347-A1 | INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | GPR119, INSR, GPR65 | TRPV1 281/4885NAMPT 2690/4885PRSS1 3433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.