Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16739387 | 0.84 | KDR (0.40) | MAPTNPC1RAB9ARXFP1ALDH1A1 | |
| SCHEMBL16739386 | 0.69 | TERT (0.49) | MAPTNPC1RAB9ARXFP1ALDH1A1 | |
| SCHEMBL16739391 | 0.69 | TERT (0.49) | MAPTNPC1RAB9ARXFP1PSMB5 | |
| SCHEMBL18226915 | 0.68 | TERT (0.46) | MAPTNPC1RAB9ARXFP1ALDH1A1 | |
| SCHEMBL20145907 | 0.66 | TERT (0.45) | MAPTNPC1ALDH1A1CFTRKDM4E | |
| SCHEMBL16739382 | 0.64 | EGFR (0.48) | NPC1RAB9ARXFP1L3MBTL1PSMB5 | |
| SCHEMBL4553044 | 0.61 | AR (0.51) | MAPTNPC1RXFP1ALDH1A1CFTR | |
| SCHEMBL29279330 | 0.61 | RAB9A (0.41) | MAPTNPC1RAB9ARXFP1ALDH1A1 | |
| SCHEMBL7879959 | 0.61 | BRD4 (0.56) | MAPTALDH1A1KDM4ETERTAPP | |
| SCHEMBL28890754 | 0.60 | ALDH1A1 (0.50) | MAPTALDH1A1PKML3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9873670-B2 | Arylquinoline and analog compounds and use thereof to treat cancer | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2018-01-23 | — | — | US | disclosed |
| US-20160280652-A1 | ARYLQUINOLINE AND ANALOG COMPOUNDS AND USE THEREOF TO TREAT CANCER | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2016-09-29 | — | — | US | disclosed |
| WO-2015077550-A1 | ARYLQUINOLINE AND ANALOG COMPOUNDS AND USE THEREOF TO TREAT CANCER | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2015-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280652-A1 | ARYLQUINOLINE AND ANALOG COMPOUNDS AND USE THEREOF TO TREAT CANCER | CASP4, BAD, BID | MAPT 3195/4885NPC1 2709/4885RAB9A 2008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.