Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.43 |
| ▸ | VDR | P11473 | 6/20 | 0.40 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 2/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16747538 | 0.98 | HMGCR (0.44) | HMGCRVDRCYP24A1LPLLIPG | |
| SCHEMBL2108199 | 0.85 | HMGCR (0.35) | HMGCRVDRCYP24A1 | |
| SCHEMBL31529676 | 0.78 | LPL (0.51) | LPLLIPGPPARGPPARA | |
| SCHEMBL2108198 | 0.78 | FFAR1 (0.39) | HMGCRVDRCYP24A1FFAR1 | |
| SCHEMBL16747397 | 0.78 | PPARG (0.34) | LPLLIPGPPARGPPARA | |
| SCHEMBL16747506 | 0.76 | PPARG (0.33) | LPLLIPGPPARGPPARA | |
| SCHEMBL236362 | 0.76 | CYP4F2 (0.43) | LPLLIPGPTPN1FFAR1CA12 | |
| SCHEMBL6155393 | 0.75 | PTGS2 (0.49) | HMGCRVDRCYP24A1 | |
| SCHEMBL4557607 | 0.73 | L3MBTL1 (0.48) | — | |
| SCHEMBL15782885 | 0.71 | TAAR1 (0.52) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3072873-B1 | VITAMIN D ANALOGUES OF PHARMACEUTICAL INTEREST | UNIV SANTIAGO COMPOSTELA (ES) | 2019-02-20 | — | — | EP | disclosed |
| US-9663429-B2 | Vitamin D analogues of pharmaceutical interest | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2017-05-30 | — | — | US | disclosed |
| US-9663429-B2 | Vitamin D analogues of pharmaceutical interest | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2017-05-30 | — | — | US | disclosed |
| US-20160297731-A1 | VITAMIN D ANALOGUES OF PHARMACEUTICAL INTEREST | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2016-10-13 | — | — | US | disclosed |
| US-20160297731-A1 | VITAMIN D ANALOGUES OF PHARMACEUTICAL INTEREST | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2016-10-13 | — | — | US | disclosed |
| EP-3072873-A1 | VITAMIN D ANALOGUES OF PHARMACEUTICAL INTEREST | Universidade De Santiago De Compostela (ES) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015075291-A1 | VITAMIN D ANALOGUES OF PHARMACEUTICAL INTEREST | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2015-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297731-A1 | VITAMIN D ANALOGUES OF PHARMACEUTICAL INTEREST | CYP24A1, VDR, CYP2R1 | HMGCR 113/4885VDR 2/4885CYP24A1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.