Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 6/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16747415 | 0.85 | HMGCR (0.43) | HMGCRVDRCYP24A1 | |
| SCHEMBL16747538 | 0.84 | HMGCR (0.44) | HMGCRVDRCYP24A1 | |
| SCHEMBL31529676 | 0.66 | LPL (0.51) | — | |
| SCHEMBL16747397 | 0.66 | PPARG (0.34) | — | |
| SCHEMBL2108198 | 0.66 | FFAR1 (0.39) | HMGCRVDRCYP24A1 | |
| SCHEMBL6884922 | 0.66 | HMGCR (0.33) | HMGCRVDRCYP24A1 | |
| SCHEMBL6155376 | 0.65 | VDR (0.32) | VDR | |
| SCHEMBL6154939 | 0.65 | HMGCR (0.54) | HMGCRVDRCYP24A1 | |
| SCHEMBL16747506 | 0.65 | PPARG (0.33) | — | |
| SCHEMBL236362 | 0.65 | CYP4F2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | claimed |
| US-11730682-B2 | Self-standing cosmetic sheet | L'OREAL (FR) | 2023-08-22 | — | — | US | disclosed |
| EP-2836187-B1 | SELF-STANDING COSMETIC SHEET | OREAL (FR) | 2021-12-08 | — | — | EP | disclosed |
| US-20180235849-A1 | SELF-STANDING COSMETIC SHEET | L'OREAL (FR) | 2018-08-23 | — | — | US | disclosed |
| US-9949897-B2 | Self-standing cosmetic sheet | L'OREAL (FR) | 2018-04-24 | — | — | US | disclosed |
| US-20150209243-A1 | SELF-STANDING COSMETIC SHEET | L'OREAL (FR) | 2015-07-30 | — | — | US | disclosed |
| EP-1658838-B1 | Emulsification system for use in cosmetics | ORÉAL L (FR) | 2014-07-02 | — | — | EP | disclosed |
| US-8158136-B2 | Emulsification system for use in cosmetics | L'ORÉAL (FR) | 2012-04-17 | — | — | US | disclosed |
| US-20070025939-A1 | cosmetic compositions containing hydroquinone and various sunscreen agents | L'OREAL S.A. (FR) | 2007-02-01 | — | — | US | disclosed |
| US-20070025937-A1 | Cosmetic compositions containing hydroquinone | L'OREAL S.A. (FR) | 2007-02-01 | — | — | US | disclosed |
| US-20060233736-A1 | Cosmetic compositions containing mono-hydroxyl substituted amines and acid derivatives | L'OREAL (FR) | 2006-10-19 | — | — | US | disclosed |
| EP-1658838-A1 | Emulsification system for use in cosmetics | L'OREAL (FR) | 2006-05-24 | — | — | EP | disclosed |
| US-20060039936-A1 | Emulsification system for use in cosmetics | L'OREAL (FR) | 2006-02-23 | — | — | US | disclosed |
| US-20050169945-A1 | Composition for protecting keratin material, process of making, uses thereof | L'OREAL (FR) | 2005-08-04 | — | — | US | disclosed |
| EP-1559398-A1 | Process for preparing a composition for the cosmetic treatment of keratinous materials on the basis of a pressurised fluid and vitamins | L'OREAL (FR) | 2005-08-03 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| US-20020197289-A1 | Compositions and methods for combating the appearance of ageing | L'OREAL (FR) | 2002-12-26 | — | — | US | disclosed |
| EP-1262168-A1 | Composition containing fibres to combat the skin aging process | L'OREAL (FR) | 2002-12-04 | — | — | EP | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060233736-A1 | Cosmetic compositions containing mono-hydroxyl substituted amines and acid derivatives | TYR, PHOSPHO1, DDC | HMGCR 1495/4885VDR 1370/4885CYP24A1 809/4885 |
| US-20020197289-A1 | Compositions and methods for combating the appearance of ageing | CYP24A1, CYP27B1, CYP2R1 | HMGCR 283/4885VDR 4/4885CYP24A1 1/4885 |
| US-20070025939-A1 | cosmetic compositions containing hydroquinone and various sunscreen agents | DHX15, HSPA4L, DDX3X | HMGCR 1972/4885VDR 863/4885CYP24A1 236/4885 |
| US-20150209243-A1 | SELF-STANDING COSMETIC SHEET | CUTA, SUCLG1, SIGLEC7 | HMGCR 691/4885VDR 4601/4885CYP24A1 3786/4885 |
| US-20180235849-A1 | SELF-STANDING COSMETIC SHEET | CUTA, DSG1, SUCLG1 | HMGCR 565/4885VDR 4085/4885CYP24A1 2442/4885 |
| US-11730682-B2 | Self-standing cosmetic sheet | CUTA, DSG1, SUCLG1 | HMGCR 565/4885VDR 4085/4885CYP24A1 2442/4885 |
| US-20050169945-A1 | Composition for protecting keratin material, process of making, uses thereof | KRT18, PROC, CUTA | HMGCR 1113/4885VDR 514/4885CYP24A1 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.