Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915491 | 0.84 | SMYD3 (0.45) | MEN1KMT2ASMYD3LMNASMN1; SMN2 | |
| SCHEMBL9915484 | 0.83 | MAPT (0.49) | MEN1KMT2ASMYD3LMNASMN1; SMN2 | |
| SCHEMBL9915519 | 0.81 | MEN1 (0.44) | MEN1KMT2ASMYD3LMNASMN1; SMN2 | |
| SCHEMBL15279079 | 0.76 | TLR7 (0.45) | MEN1KMT2ALMNARAB9AHPGD | |
| SCHEMBL15279003 | 0.75 | DAO (0.43) | LMNA | |
| SCHEMBL9944295 | 0.72 | MAPT (0.54) | MEN1KMT2ALMNASMN1; SMN2STAT3 | |
| SCHEMBL15279000 | 0.71 | L3MBTL1 (0.41) | MAPTKDM4E | |
| SCHEMBL16748804 | 0.71 | NR1H4 (0.46) | KMT2ALMNASMN1; SMN2NR1H4TSHR | |
| SCHEMBL9915523 | 0.71 | C5AR1 (0.39) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6347341 | 0.69 | RAB9A (0.65) | MEN1KMT2ALMNASMN1; SMN2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646436-B1 | MONOBACTAMS | PFIZER (US) | 2015-05-27 | — | — | EP | disclosed |