SCHEMBL16755458

SCHEMBL16755458

Ic1ccc2ccc3ccccc3c2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
HSD17B10 Q99714 3/20 0.64
CYP1B1 Q16678 2/20 0.64
HIF1A Q16665 1/20 0.64
CYP2A6 P11509 2/20 0.60
TSHR P16473 2/20 0.60
TDP1 Q9NUW8 1/20 0.60
HPRT1 P00492 3/20 0.55
CYP1A2 P05177 4/20 0.47
HPGD P15428 2/20 0.47
PAX8 Q06710 1/20 0.44
CASP3 P42574 1/20 0.42
GFER P55789 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
ERBB2 P04626 1/20 0.40
FYN P06241 1/20 0.40
MAOA P21397 1/20 0.40
ACHE P22303 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19558294 0.95 HPRT1 (0.64) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
SCHEMBL1527553 0.88 ALDH1A1 (0.61) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
SCHEMBL23783950 0.86 HPRT1 (0.64) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
SCHEMBL25829004 0.84 HSD17B10 (0.46) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
SCHEMBL10860356 0.82 AKR1B1 (0.45) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
SCHEMBL19802366 0.80 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
SCHEMBL13749724 0.79 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
Dibenz[A,H]Anthracene SCHEMBL29392838 0.78 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
Dibenz[A,H]Anthracene SCHEMBL29777008 0.78 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
Dibenz[A,H]Anthracene SCHEMBL156100 0.78 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035339-A1 TETRAHYDRONAPHTHALENE DERIVATIVE ATRANSEN PHARMA LTD (JP) 2026-02-05 US disclosed
EP-4501906-A1 TETRAHYDRONAPHTHALENE DERIVATIVE Atransen Pharma Ltd. (JP) 2025-02-05 EP disclosed
CN-118974007-A Tetrahydronaphthalene derivatives 阿创森制药股份有限公司 2024-11-15 CN disclosed
EP-4324831-A1 ARYLAMINE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS Shaanxi Lighte Optoelectronics Material Co., Ltd. (CN) 2024-02-21 EP disclosed
US-20240023356-A1 ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-18 US disclosed
US-11864400-B2 Organic light-emitting device and electronic apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-02 US disclosed
US-20230380267-A1 COMPOUNDS FOR STRUCTURING FUNCTIONAL LAYERS OF ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-11-23 US disclosed
US-11818932-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-14 US disclosed
US-20230354694-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, ELECTONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-02 US disclosed
US-11802116-B2 Diamine compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-31 US disclosed
US-20170062720-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-02 US disclosed
US-20170054085-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-23 US disclosed
EP-3127988-A1 ORGANIC LIGHT-EMITTING DEVICE LG Chem, Ltd. (KR) 2017-02-08 EP disclosed
EP-3127987-A1 ORGANIC LIGHT-EMITTING DEVICE LG Chem, Ltd. (KR) 2017-02-08 EP disclosed
EP-3127901-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2017-02-08 EP disclosed
US-20170033297-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-02 US disclosed
US-20150155491-A1 PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-06-04 US disclosed
US-20150155491-A1 PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-06-04 US disclosed
US-20150155491-A1 PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-06-04 US disclosed
CN-104364245-A Phenanthrene compounds for organic electronic devices MERCK PATENT GMBH 2015-02-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170062720-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LRRK2, SLC18A1, CCNT1 ALDH1A1 832/4885HSD17B10 2767/4885CYP1B1 447/4885
US-20150155491-A1 PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES PAH, CYP1A1, AHR ALDH1A1 1334/4885HSD17B10 1425/4885CYP1B1 11/4885
US-11802116-B2 Diamine compound and organic light-emitting device including the same AOC1, ODC1, DDT ALDH1A1 17/4885HSD17B10 3948/4885CYP1B1 1031/4885
US-20170033297-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CCNE2, CCNE1, CCNA1 ALDH1A1 275/4885HSD17B10 3173/4885CYP1B1 188/4885
US-20260035339-A1 TETRAHYDRONAPHTHALENE DERIVATIVE LATS1, LATS2, BCAT1 ALDH1A1 1267/4885HSD17B10 548/4885CYP1B1 374/4885
US-20230354694-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, ELECTONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE INCLUDING THE LIGHT-EMITTING DEVICE LAGE3, ELP1, EML4 ALDH1A1 98/4885HSD17B10 1517/4885CYP1B1 1053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.