Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 8/20 | 0.50 |
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 3/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14961177 | 0.88 | ERN1 (0.47) | MAP4K4RXRAHSD17B10RXRBERN1 | |
| SCHEMBL14961176 | 0.88 | ERN1 (0.47) | MAP4K4RXRAHSD17B10RXRBERN1 | |
| SCHEMBL18504207 | 0.88 | HSD17B10 (0.49) | MAP4K4RXRAHSD17B10RXRBERN1 | |
| SCHEMBL12535966 | 0.88 | RXRA (0.54) | RXRAHSD17B10RXRBERN1TRIM24 | |
| SCHEMBL10260784 | 0.88 | RXRA (0.54) | RXRAHSD17B10RXRBERN1TRIM24 | |
| SCHEMBL16769649 | 0.88 | RXRA (0.54) | RXRAHSD17B10RXRBERN1TRIM24 | |
| SCHEMBL16769640 | 0.87 | RXRA (0.49) | MAP4K4RXRAHSD17B10RXRBERN1 | |
| SCHEMBL12780511 | 0.86 | HSD17B10 (0.56) | RXRAHSD17B10RXRBERN1TRIM24 | |
| SCHEMBL16749641 | 0.86 | MAP4K4 (0.57) | MAP4K4RXRARXRBEGFR | |
| SCHEMBL15119807 | 0.84 | RXRA (0.51) | RXRAHSD17B10RXRBERN1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951095-B2 | Chromium metal organic frameworks and synthesis of metal organic frameworks | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2018-04-24 | — | — | US | disclosed |
| US-9724668-B2 | Iron metal organic framework materials | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-08-08 | — | — | US | disclosed |
| US-20170050995-A1 | Chromium Metal Organic Frameworks and Synthesis of Metal Organic Frameworks | THE TEXAS A&M UNIVERSITY SYSTEM | 2017-02-23 | — | — | US | disclosed |
| US-20160346759-A1 | Iron Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2016-12-01 | — | — | US | disclosed |
| US-9102691-B2 | Aluminum metal organic framework materials | TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-08-11 | — | — | US | disclosed |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050995-A1 | Chromium Metal Organic Frameworks and Synthesis of Metal Organic Frameworks | OXGR1, TFRC, PICALM | MAP4K4 4069/4885RXRA 2502/4885HSD17B10 3807/4885 |
| US-20160346759-A1 | Iron Metal Organic Framework Materials | TFRC, FTH1, FECH | MAP4K4 3413/4885RXRA 4751/4885HSD17B10 4292/4885 |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | AS3MT, ORAI2, ORAI3 | MAP4K4 3700/4885RXRA 4007/4885HSD17B10 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.