Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.62 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.54 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16749640 | 0.89 | RARB (0.68) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL16769641 | 0.81 | MAPT (0.44) | RARBPTPN11 | |
| SCHEMBL16769640 | 0.78 | RXRA (0.49) | RARB | |
| SCHEMBL4185457 | 0.78 | RARB (1.00) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL5828640 | 0.78 | RARB (1.00) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL641904 | 0.78 | RARB (1.00) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL7172427 | 0.78 | RARB (1.00) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL8943017 | 0.78 | RARB (1.00) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL5858775 | 0.78 | RARB (1.00) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL8532269 | 0.78 | RARB (1.00) | RARBPTPN11TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951095-B2 | Chromium metal organic frameworks and synthesis of metal organic frameworks | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2018-04-24 | — | — | US | disclosed |
| US-9724668-B2 | Iron metal organic framework materials | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-08-08 | — | — | US | disclosed |
| US-20170050995-A1 | Chromium Metal Organic Frameworks and Synthesis of Metal Organic Frameworks | THE TEXAS A&M UNIVERSITY SYSTEM | 2017-02-23 | — | — | US | disclosed |
| US-20160346759-A1 | Iron Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2016-12-01 | — | — | US | disclosed |
| US-9102691-B2 | Aluminum metal organic framework materials | TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-08-11 | — | — | US | disclosed |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050995-A1 | Chromium Metal Organic Frameworks and Synthesis of Metal Organic Frameworks | OXGR1, TFRC, PICALM | RARB 2639/4885PTPN11 3759/4885TP53 292/4885 |
| US-20160346759-A1 | Iron Metal Organic Framework Materials | TFRC, FTH1, FECH | RARB 4562/4885PTPN11 3946/4885TP53 1470/4885 |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | AS3MT, ORAI2, ORAI3 | RARB 4394/4885PTPN11 3954/4885TP53 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.