Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12384276 | 0.90 | MEN1 (0.44) | RXRACA1CA2KDM4ECA12 | |
| SCHEMBL12349931 | 0.88 | CA12 (0.42) | CA1CA2KDM4ECA12CA3 | |
| SCHEMBL39734 | 0.86 | CA1 (0.60) | RXRACA1CA2KDM4ECA12 | |
| 3,5-Dimethoxybenzoic Acid SCHEMBL503889 | 0.86 | RXRA (0.64) | RXRACA1CA2ABCG2KDM4E | |
| SCHEMBL25508690 | 0.84 | RXRA (0.58) | RXRACA1CA2ABCG2KDM4E | |
| Hydrochloric Acid SCHEMBL3361588 | 0.84 | CA1 (0.58) | RXRACA1CA2KDM4ECA12 | |
| 3,5-Dimethoxybenzoic Acid SCHEMBL20592058 | 0.84 | RXRA (0.62) | RXRACA1CA2ABCG2KDM4E | |
| Hydrochloric Acid SCHEMBL19118500 | 0.84 | CA1 (0.58) | RXRACA1CA2KDM4ECA12 | |
| 3,5-Dimethoxybenzoic Acid SCHEMBL5668197 | 0.84 | RXRA (0.62) | RXRACA1CA2ABCG2KDM4E | |
| SCHEMBL2092735 | 0.84 | ALDH1A1 (0.58) | ABCG2PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951095-B2 | Chromium metal organic frameworks and synthesis of metal organic frameworks | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2018-04-24 | — | — | US | disclosed |
| US-9724668-B2 | Iron metal organic framework materials | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-08-08 | — | — | US | disclosed |
| US-20170050995-A1 | Chromium Metal Organic Frameworks and Synthesis of Metal Organic Frameworks | THE TEXAS A&M UNIVERSITY SYSTEM | 2017-02-23 | — | — | US | disclosed |
| US-20160346759-A1 | Iron Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2016-12-01 | — | — | US | disclosed |
| US-9102691-B2 | Aluminum metal organic framework materials | TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-08-11 | — | — | US | disclosed |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050995-A1 | Chromium Metal Organic Frameworks and Synthesis of Metal Organic Frameworks | OXGR1, TFRC, PICALM | RXRA 2502/4885CA1 13/4885CA2 7/4885 |
| US-20160346759-A1 | Iron Metal Organic Framework Materials | TFRC, FTH1, FECH | RXRA 4751/4885CA1 514/4885CA2 405/4885 |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | AS3MT, ORAI2, ORAI3 | RXRA 4007/4885CA1 94/4885CA2 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.