Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.70 |
| ▸ | MEN1 | O00255 | 6/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | RAF1 | P04049 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | BRAF | P15056 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19427492 | 0.88 | MEN1 (0.84) | MAPTMEN1KMT2AGAATP53 | |
| SCHEMBL8370207 | 0.86 | GSK3A (0.66) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL938321 | 0.85 | RAF1 (0.74) | MAPTRAF1ALDH1A1KDM4EBRAF | |
| SCHEMBL4243486 | 0.85 | RAF1 (0.61) | MAPTMEN1KMT2AGAATP53 | |
| SCHEMBL6760901 | 0.85 | EPHX2 (0.56) | MAPTMEN1KMT2AGAATP53 | |
| SCHEMBL3476076 | 0.85 | RAF1 (0.61) | MAPTMEN1KMT2AGAATP53 | |
| SCHEMBL4247303 | 0.85 | MEN1 (0.64) | MAPTMEN1KMT2AGAATP53 | |
| SCHEMBL5445313 | 0.84 | RAF1 (0.60) | MAPTMEN1KMT2AGAATP53 | |
| SCHEMBL31440788 | 0.83 | KMT2A (0.61) | MAPTMEN1KMT2AMAPK1POLB | |
| SCHEMBL19427718 | 0.83 | MAPT (0.79) | MAPTMEN1KMT2AGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150150878-A1 | Methods For Inhibiting Viruses By Targeting Cathepsin-L Cleavage Sites In The Viruses' Glycoproteins | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150150878-A1 | Methods For Inhibiting Viruses By Targeting Cathepsin-L Cleavage Sites In The Viruses' Glycoproteins | CTSL, CTSH, CTSV | MAPT 3447/4885MEN1 4435/4885KMT2A 4587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.