Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAT2A | P31153 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23633379 | 0.88 | ALDH1A1 (0.65) | PSMD14L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL16783127 | 0.87 | KDM4E (0.51) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL23633377 | 0.84 | TP53 (0.50) | PSMD14L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL16783194 | 0.83 | ALDH1A1 (0.55) | PSMD14L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL16783126 | 0.83 | RXFP1 (0.55) | PSMD14L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL23633374 | 0.83 | OPRM1 (0.48) | PSMD14L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL16783111 | 0.82 | L3MBTL1 (0.49) | PSMD14L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL16783157 | 0.81 | L3MBTL1 (0.79) | PSMD14L3MBTL1KDM4EKMT2AMAT2A | |
| SCHEMBL16783143 | 0.81 | RXFP1 (0.47) | PSMD14L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL16783145 | 0.81 | OPRM1 (0.51) | PSMD14L3MBTL1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150164910-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-06-18 | — | — | US | disclosed |
| US-20150164910-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-06-18 | — | — | US | disclosed |
| US-20150164910-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150164910-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE | EIF2AK2, RNASE1, HAVCR2 | PSMD14 2011/4885L3MBTL1 561/4885KDM4E 2857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.