Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 3/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 7/20 | 0.43 |
| ▸ | BACE1 | P56817 | 7/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795154 | 0.83 | POLB (0.56) | POLBMEN1KMT2AMITF | |
| SCHEMBL16795306 | 0.82 | CARM1 (0.47) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL4220280 | 0.77 | POLB (0.65) | CARM1PRMT6ACHEBACE1POLB | |
| SCHEMBL16795137 | 0.75 | ACHE (0.34) | CARM1PRMT6ACHEBACE1DRD2 | |
| SCHEMBL20766436 | 0.74 | MAP4K4 (0.54) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL3457833 | 0.74 | MEN1 (0.59) | CARM1PRMT6ACHEBACE1POLB | |
| SCHEMBL16795184 | 0.73 | BCHE (0.52) | CARM1PRMT6ACHEBACE1POLB | |
| SCHEMBL16795390 | 0.73 | NOS2 (0.53) | MAP4K4 | |
| SCHEMBL4983041 | 0.72 | EPHX1 (0.52) | POLBMEN1KMT2A | |
| SCHEMBL20766403 | 0.72 | ALDH1A1 (0.71) | CARM1PRMT6ACHEBACE1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |