Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 8/20 | 0.43 |
| ▸ | BACE1 | P56817 | 8/20 | 0.43 |
| ▸ | BCHE | P06276 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795291 | 0.82 | CARM1 (0.47) | CARM1PRMT6ACHEBACE1BCHE | |
| SCHEMBL16795154 | 0.80 | POLB (0.56) | HRH3MEN1KMT2A | |
| SCHEMBL16795221 | 0.77 | HRH3 (0.40) | CARM1PRMT6HRH3ACHEBACE1 | |
| SCHEMBL26268982 | 0.70 | POLB (0.62) | HRH3ACHEMEN1KMT2A | |
| SCHEMBL16795141 | 0.70 | CXCR3 (0.51) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL16795206 | 0.70 | KCNH2 (0.49) | HRH3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL31567098 | 0.69 | POLB (0.66) | HRH3MEN1KMT2A | |
| SCHEMBL16795145 | 0.66 | L3MBTL1 (0.51) | HRH3 | |
| SCHEMBL16795223 | 0.66 | SIGMAR1 (0.56) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL16256975 | 0.65 | SIGMAR1 (0.61) | CARM1PRMT6ACHEBACE1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |