SCHEMBL1680392

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4913335	0.75	TSHR (0.41)	MAOBALDH1A1ALOX15HCAR2TSHR
	SCHEMBL4903260	0.74	MAOB (0.43)	MAOAMAOBALDH1A1TSHRSMN1; SMN2
	SCHEMBL28325265	0.73	ALDH1A1 (0.49)	ALDH1A1ALOX15HCAR2TSHRSMN1; SMN2
	SCHEMBL1680931	0.72	LOXL2 (0.45)	MAOAMAOBALDH1A1CYP2A6TSHR
	SCHEMBL1680845	0.72	TSHR (0.45)	ALDH1A1HCAR2TSHRLMNAL3MBTL1
	SCHEMBL27792150	0.72	TSHR (0.50)	ALDH1A1ALOX15HCAR2TSHRLMNA
	SCHEMBL510501	0.70	DRD2 (0.52)	MAOAMAOBDRD2DRD4DRD3
	SCHEMBL25244587	0.70	MAOB (0.51)	MAOAMAOBALDH1A1LMNASMN1; SMN2
	SCHEMBL7369619	0.67	TSHR (0.62)	MAOAMAOBALDH1A1CYP2A6TSHR
	SCHEMBL18003310	0.67	DRD4 (0.43)	MAOAMAOBDRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.