SCHEMBL1680931

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680845	0.82	TSHR (0.45)	IDO1AGXTTSHRALDH1A1CA1
	SCHEMBL4903260	0.80	MAOB (0.43)	MAOBIDO1AGXTTSHRALDH1A1
	SCHEMBL4913335	0.78	TSHR (0.41)	MAOBIDO1AGXTTSHRALDH1A1
	SCHEMBL27792150	0.74	TSHR (0.50)	IDO1AGXTTSHRALDH1A1CA1
	SCHEMBL4906140	0.73	IDO1 (0.46)	MAOBIDO1AGXTTSHRALDH1A1
	SCHEMBL1680392	0.72	MAOA (0.44)	MAOBIDO1TSHRALDH1A1SMN1; SMN2
	SCHEMBL28325265	0.72	ALDH1A1 (0.49)	IDO1AGXTTSHRALDH1A1CA1
	SCHEMBL1680504	0.68	LOXL2 (0.50)	LOXL2ALDH1A1TAAR1CA1CA2
	SCHEMBL4912485	0.67	MAOB (0.41)	MAOBIDO1AGXTTSHRALDH1A1
	SCHEMBL4912600	0.67	IDO1 (0.39)	MAOBIDO1AGXTTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.