SCHEMBL1680484

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17138214	0.84	KDM4E (0.51)	MAOBALDH1A1KDM4EMTNR1A
	SCHEMBL20706014	0.83	CYP4F2 (0.50)	MAOBPPARD
	SCHEMBL14540810	0.80	CYP3A4 (0.58)	MAOBALDH1A1KDM4EMTNR1ACYP3A4
	SCHEMBL3772898	0.79	MAOB (0.46)	MAOBNOS1NOS2ENPP2LOXL2
	SCHEMBL12879334	0.78	LMNA (0.49)	MAOBALDH1A1KDM4EMTNR1A
	SCHEMBL791805	0.78	LMNA (0.53)	MAOBALDH1A1KDM4EMTNR1A
	SCHEMBL12482566	0.78	NOS1 (0.48)	MAOBNOS1NOS2ENPP2LOXL2
	SCHEMBL3768879	0.78	KDM4E (0.49)	MAOBNOS1NOS2ALDH1A1KDM4E
	SCHEMBL3769194	0.77	AOC3 (0.46)	MAOBNOS1NOS2ENPP2CYP3A4
	SCHEMBL606214	0.75	TP53 (0.60)	MAOBNOS1NOS2ENPP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.