SCHEMBL20706014

SCHEMBL20706014

CC(C)=CCOc1cccc(CCc2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.50
CYP4A11 Q02928 1/20 0.50
PPARD Q03181 2/20 0.48
NDUFS8 O00217 1/20 0.46
COXFA4 O00483 1/20 0.46
NDUFAB1 O14561 1/20 0.46
NDUFA1 O15239 1/20 0.46
NDUFS4 O43181 1/20 0.46
NDUFB5 O43674 1/20 0.46
NDUFB3 O43676 1/20 0.46
NDUFC1 O43677 1/20 0.46
NDUFA2 O43678 1/20 0.46
NDUFS5 O43920 1/20 0.46
NDUFS7 O75251 1/20 0.46
NDUFS2 O75306 1/20 0.46
NDUFS6 O75380 1/20 0.46
NDUFB1 O75438 1/20 0.46
NDUFS3 O75489 1/20 0.46
NDUFB6 O95139 1/20 0.46
NDUFA3 O95167 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17138214 0.83 KDM4E (0.51) MAOB
SCHEMBL1680484 0.83 MAOB (0.45) PPARDMAOB
SCHEMBL1135899 0.81 NDUFS8 (0.49) NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4
SCHEMBL20706016 0.78 MAOB (0.57) NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4
SCHEMBL791805 0.77 LMNA (0.53) MAOB
SCHEMBL12879334 0.77 LMNA (0.49) MAOBDRD2
SCHEMBL14540810 0.76 CYP3A4 (0.58) MAOB
SCHEMBL3316075 0.75 KMT2A (0.60) MAOB
SCHEMBL10235885 0.73 KMT2A (0.54) CYP4F2CYP4A11BCHEFFAR1
SCHEMBL29955979 0.73 ENPP2 (0.54) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11352310-B2 Prenylated hydroxystilbenes Kynan Duke IP, LLC (US) 2022-06-07 US disclosed
US-20200331833-A1 PRENYLATED HYDROXYSTILBENES THE UNIVERSITY OF SYDNEY (AU) 2020-10-22 US disclosed
US-10196335-B2 Prenylated hydroxystilbenes THE UNIVERSITY OF SYDNEY (AU) 2019-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10196335-B2 Prenylated hydroxystilbenes HMGB2, CYP51A1, CYP8B1 CYP4F2 339/4885CYP4A11 126/4885PPARD 262/4885
US-20200331833-A1 PRENYLATED HYDROXYSTILBENES HSD11B1, HSD3B1, CYP8B1 CYP4F2 304/4885CYP4A11 34/4885PPARD 398/4885
US-11352310-B2 Prenylated hydroxystilbenes HSD11B1, HSD3B1, CYP8B1 CYP4F2 304/4885CYP4A11 34/4885PPARD 398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.