SCHEMBL1680700

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL920992	0.82	TEAD4 (0.42)	MAOBMAOACYP2C9CYP2C19CYP1A2
	SCHEMBL1680601	0.82	GAA (0.42)	MAOBMAOACYP2C9CYP2C19MEN1
	SCHEMBL13067606	0.82	MAOA (0.38)	MAOBMAOACYP2C9CYP2C19CYP1A2
	SCHEMBL922635	0.81	CYP2E1 (0.48)	MAOACYP2C9CYP2C19LTA4HLOX
	SCHEMBL1680718	0.80	PNMT (0.41)	MAOBCYP2C9CYP2C19CYP1A2SMN1; SMN2
	SCHEMBL13026622	0.78	HTR2A (0.36)	MAOBMAOACYP2C9CYP2C19CYP1A2
	SCHEMBL1680855	0.72	DPP4 (0.42)	MAOACYP2C9CYP2C19ALDH1A1HPGD
	SCHEMBL1680519	0.70	MAOB (0.39)	MAOBCYP2C9CYP2C19CYP1A2CYP2D6
	SCHEMBL1680329	0.70	MAOB (0.39)	MAOBCYP2C9CYP2C19MAPTLOX
	SCHEMBL920993	0.70	ALDH1A1 (0.46)	CYP2C9CYP2C19MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.