SCHEMBL1680757

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16453461	0.88	MAOB (0.45)	LOXL2LOXMAOBKDM4EMEN1
	SCHEMBL30931699	0.85	LOXL2 (0.65)	LOXL2LOXMAOB
	SCHEMBL8278886	0.83	LMNA (0.45)	MAOBKDM4EMEN1KMT2ACYP11B1
	SCHEMBL510115	0.83	MEN1 (0.53)	MAOBMEN1KMT2ACYP11B1CYP11B2
	SCHEMBL14149731	0.83	CYP11B1 (0.39)	LOXL2LOXMAOBKDM4EMEN1
	SCHEMBL3887646	0.83	GABRA5 (0.50)	MAOBKDM4ENOS2
	SCHEMBL8278888	0.83	LOX (0.43)	LOXL2LOXKDM4EMEN1NOS3
	SCHEMBL15177152	0.82	GPR84 (0.41)	LOXL2LOXKDM4EMEN1NOS3
	SCHEMBL8279828	0.82	PDE2A (0.52)	LOXL2LOXMAOBKDM4E
	SCHEMBL23316746	0.81	LOXL2 (0.59)	LOXL2LOXMAOBKARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.