SCHEMBL1680877

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680753	0.83	ALDH1A1 (0.47)	ALDH1A1TSHRMAOAMAOBDAO
	SCHEMBL509869	0.82	ALDH1A1 (0.53)	ALDH1A1TSHRMAOAMAOBDAO
	SCHEMBL1244130	0.81	ALDH1A1 (0.57)	ALDH1A1TSHRLMNAKDM4ECTSL
	SCHEMBL17398481	0.81	ALDH1A1 (0.46)	ALDH1A1TSHRMAOAMAOBTAAR1
	SCHEMBL4498539	0.76	TAAR1 (0.50)	MAOAMAOBDAOTAAR1IDO1
	SCHEMBL1680634	0.76	TAAR1 (0.50)	MAOBDAOTAAR1IDO1AGXT
	SCHEMBL4164573	0.74	NR3C2 (0.46)	ALDH1A1MAOBLMNASMN1; SMN2HCAR2
	SCHEMBL4674508	0.74	ALDH1A1 (0.46)	ALDH1A1MAOAMAOBSMN1; SMN2HCAR2
	SCHEMBL7328684	0.72	ALDH1A1 (0.64)	ALDH1A1LMNAKDM4ESMN1; SMN2TDP1
	SCHEMBL17521499	0.71	MAOA (0.54)	ALDH1A1MAOAMAOBDAOTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.