SCHEMBL1680889

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3402865	0.87	MMP13 (0.67)	L3MBTL1SMN1; SMN2HPGDROCK2KCNQ3
	SCHEMBL1680768	0.86	FFAR1 (0.60)	L3MBTL1FFAR1SMN1; SMN2MAPK14HPGD
	SCHEMBL4067449	0.85	L3MBTL1 (1.00)	L3MBTL1SMN1; SMN2NPC1RAB9AHPGD
	SCHEMBL16343160	0.84	L3MBTL1 (0.78)	L3MBTL1SMN1; SMN2NPC1RAB9AROCK2
	SCHEMBL27841827	0.83	L3MBTL1 (0.76)	L3MBTL1SMN1; SMN2NPC1RAB9AHPGD
	SCHEMBL1331793	0.80	NPC1 (0.79)	L3MBTL1SMN1; SMN2NPC1RAB9AKCNQ3
	SCHEMBL1681281	0.79	FFAR1 (0.60)	FFAR1SMN1; SMN2MAPK14HPGDROCK2
	SCHEMBL5697540	0.78	PSMD14 (0.54)	FFAR1SMN1; SMN2MAPK14HPGDROCK2
	SCHEMBL31023556	0.78	L3MBTL1 (0.84)	L3MBTL1SMN1; SMN2NPC1RAB9AROCK2
	SCHEMBL1680708	0.77	ROCK2 (0.63)	FFAR1SMN1; SMN2MAPK14HPGDROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.