Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL31432631 | 0.99 | ALDH1A1 (0.49) | ALDH1A1HPGDNPSR1L3MBTL1BRD4 | |
| SCHEMBL11949311 | 0.86 | RAB9A (0.48) | ALDH1A1HPGDNPSR1L3MBTL1PKM | |
| Bromide SCHEMBL693845 | 0.85 | NPC1 (0.47) | ALDH1A1HPGDNPSR1L3MBTL1PKM | |
| Hydrochloric Acid SCHEMBL1373732 | 0.85 | PKM (0.47) | ALDH1A1HPGDNPSR1L3MBTL1PKM | |
| Bromide SCHEMBL555083 | 0.81 | CA12 (0.43) | BRD4PKMRAB9ANPC1 | |
| SCHEMBL15836427 | 0.80 | ALDH1A1 (0.46) | ALDH1A1NPSR1L3MBTL1RAB9AKDM4E | |
| Bromide SCHEMBL15820807 | 0.79 | ACHE (0.48) | ALDH1A1NPSR1L3MBTL1RAB9AKDM4E | |
| SCHEMBL11949310 | 0.77 | ACHE (0.56) | ALDH1A1NPSR1L3MBTL1PKMRAB9A | |
| SCHEMBL5307716 | 0.74 | ALDH1A1 (0.53) | ALDH1A1NPSR1L3MBTL1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL7307884 | 0.73 | ALDH1A1 (0.56) | ALDH1A1NPSR1L3MBTL1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951012-B2 | Process for the preparation of (3R,4R)-(1-benzyl-4-methylpiperidin-3-yl)-methylamine | UNICHEM LABORATORIES LIMITED (IN) | 2018-04-24 | — | — | US | disclosed |
| US-20180037551-A1 | Process for the Preparation of (3R,4R)-(1-BENZYL-4-METHYLPIPERIDIN-3-YL)-METHYLAMINE | UNICHEM LAB LTD (IN) | 2018-02-08 | — | — | US | disclosed |
| US-20160102057-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF (3R,4R)-(1-BENZYL-4-METHYLPIPERIDIN-3-YL)-METHYLAMINE | UNICHEM LABORATORIES LIMITED (IN) | 2016-04-14 | — | — | US | disclosed |
| US-20160102057-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF (3R,4R)-(1-BENZYL-4-METHYLPIPERIDIN-3-YL)-METHYLAMINE | UNICHEM LABORATORIES LIMITED (IN) | 2016-04-14 | — | — | US | disclosed |
| WO-2015087201-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF (3R,4R)-(1-BENZYL-4-METHYLPIPERIDIN-3-YL)-METHYLAMINE | UNICHEM LABORATORIES LIMITED (IN) | 2015-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037551-A1 | Process for the Preparation of (3R,4R)-(1-BENZYL-4-METHYLPIPERIDIN-3-YL)-METHYLAMINE | KDM4D, KDM4A, KDM4C | ALDH1A1 2146/4885HPGD 3454/4885NPSR1 1167/4885 |
| US-20160102057-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF (3R,4R)-(1-BENZYL-4-METHYLPIPERIDIN-3-YL)-METHYLAMINE | KDM4D, KDM4A, KDM4C | ALDH1A1 1622/4885HPGD 3583/4885NPSR1 1360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.