SCHEMBL16809663

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16809543	0.99	SIGMAR1 (0.42)	SIGMAR1HPGDTSHRTMEM97HTR1A
	SCHEMBL16809562	0.89	SIGMAR1 (0.44)	SIGMAR1
	SCHEMBL16809671	0.87	SIGMAR1 (0.44)	SIGMAR1
	SCHEMBL16809472	0.81	SIGMAR1 (0.41)	SIGMAR1HPGDTSHR
	SCHEMBL19894315	0.80	CA2 (0.37)	HPGDTSHRHTR1AADRA1BADRA1D
	SCHEMBL19894310	0.78	CA2 (0.38)	HTR1AADRA1BADRA1D
	SCHEMBL19894334	0.78	CA2 (0.36)	SIGMAR1HPGDTSHRHTR1AADRA1B
	SCHEMBL16809653	0.78	KCNH2 (0.35)	SIGMAR1HPGDTSHRHTR1AADRA1B
	SCHEMBL16809424	0.78	KCNH2 (0.55)	SIGMAR1
	SCHEMBL19894296	0.78	ALDH1A1 (0.35)	SIGMAR1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.