Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18169277 | 0.99 | CA2 (0.51) | CA2CA1HTR1AADRA1BADRA1D | |
| SCHEMBL18169343 | 0.89 | CA2 (0.40) | CA2CA1HTR1AADRA1BADRA1D | |
| SCHEMBL18169306 | 0.87 | CA2 (0.41) | CA2CA1HTR1AADRA1BADRA1D | |
| SCHEMBL16809615 | 0.84 | CA2 (0.53) | CA2CA1CA9 | |
| SCHEMBL16809703 | 0.80 | CA2 (0.51) | CA2CA1PKMLMNASMN1; SMN2 | |
| SCHEMBL18169268 | 0.79 | CA2 (0.46) | CA2CA1ALDH1A1PKMHPGD | |
| SCHEMBL18169303 | 0.79 | CA2 (0.46) | CA2CA1ALDH1A1PKMHPGD | |
| SCHEMBL16809618 | 0.79 | CA2 (0.46) | CA2CA1ALDH1A1PKMHPGD | |
| SCHEMBL16809663 | 0.77 | SIGMAR1 (0.41) | HTR1AADRA1BADRA1DADRA1AHPGD | |
| SCHEMBL16809653 | 0.77 | KCNH2 (0.35) | HTR1AADRA1BADRA1DADRA1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10081615-B2 | Sulfamate derivative compounds for use in treating or alleviating pain | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2018-09-25 | — | — | US | claimed |
| EP-3079687-B1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO-PHARM SOLUTIONS CO LTD (KR) | 2018-02-28 | — | — | EP | claimed |
| US-20160311792-A1 | Sulfamate Derivative Compounds for Use in Treating or Alleviating Pain | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2016-10-27 | — | — | US | claimed |
| US-10081615-B2 | Sulfamate derivative compounds for use in treating or alleviating pain | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2018-09-25 | — | — | US | disclosed |
| EP-3079687-B1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO-PHARM SOLUTIONS CO LTD (KR) | 2018-02-28 | — | — | EP | disclosed |
| US-20160311792-A1 | Sulfamate Derivative Compounds for Use in Treating or Alleviating Pain | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2016-10-27 | — | — | US | disclosed |
| US-20160311792-A1 | Sulfamate Derivative Compounds for Use in Treating or Alleviating Pain | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2016-10-27 | — | — | US | disclosed |
| US-20160311792-A1 | Sulfamate Derivative Compounds for Use in Treating or Alleviating Pain | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2016-10-27 | — | — | US | disclosed |
| WO-2015088272-A9 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2015-10-01 | — | — | WO | disclosed |
| WO-2015088272-A1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2015-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311792-A1 | Sulfamate Derivative Compounds for Use in Treating or Alleviating Pain | SULT2A1, SULT1A1, TRPV1 | CA2 91/4885CA1 458/4885HTR1A 761/4885 |
| US-10081615-B2 | Sulfamate derivative compounds for use in treating or alleviating pain | SULT2A1, SULT1A1, TRPV1 | CA2 91/4885CA1 458/4885HTR1A 761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.