Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | LTA4H | P09960 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11473119 | 0.98 | CYP19A1 (0.49) | CYP19A1LTA4HTSHRMEN1KMT2A | |
| SCHEMBL13895544 | 0.85 | CYP19A1 (0.59) | CYP19A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL17423720 | 0.84 | CYP19A1 (0.68) | CYP19A1LTA4HSMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL10392865 | 0.83 | P2RX3 (0.47) | CYP19A1LTA4HMEN1KMT2AHPGD | |
| SCHEMBL3413808 | 0.83 | ALDH1A1 (0.52) | CYP19A1TSHRMEN1KMT2APOLB | |
| SCHEMBL12634621 | 0.83 | SLC22A12 (0.45) | CYP19A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL19405907 | 0.81 | MAOB (0.54) | CYP19A1MAOA | |
| SCHEMBL24155920 | 0.80 | SMN1; SMN2 (0.58) | MEN1KMT2APIN1ERBB2GLA | |
| SCHEMBL21045811 | 0.79 | DGAT1 (0.44) | CYP19A1LTA4H | |
| SCHEMBL21664072 | 0.78 | KCNA3 (0.42) | GLASMN1; SMN2CHEK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141439-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-09 | — | — | WO | disclosed |
| WO-2020141439-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-09 | — | — | WO | disclosed |
| US-20200206233-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-02 | — | — | US | disclosed |
| US-20200206233-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-02 | — | — | US | disclosed |
| US-20110195999-A1 | NOVEL ANTIFUNGAL AGENT CONTAINING HETEROCYCLIC COMPOUND | NAKAMOTO KAZUTAKA | 2011-08-11 | — | — | US | disclosed |
| US-7932272-B2 | Antifungal agent containing heterocyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-04-26 | — | — | US | disclosed |
| US-20090227799-A1 | Novel Antimalarial Agent Containing Heterocyclic Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20070105943-A1 | Novel antifungal agent containing heterocyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| EP-1782811-A1 | NOVEL ANTIMALARIA AGENT CONTAINING HETEROCYCLIC COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-05-09 | — | — | EP | disclosed |
| EP-1669348-A1 | NOVEL ANTIFUNGAL AGENT COMPRISING HETEROCYCLIC COMPOUND | Eisai Co., Ltd. (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-0091464-B1 | METHOD FOR THE PREPARATION OF CYANO-HETEROCYCLES | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-04-16 | — | — | EP | disclosed |
| EP-0091464-A1 | METHOD FOR THE PREPARATION OF CYANO-HETEROCYCLES. | SCHERING AG (DE) | 1983-10-19 | — | — | EP | disclosed |
| WO-1983001446-A1 | METHOD FOR THE PREPARATION OF CYANO-HETEROCYCLES | VORBRÜGGEN, Helmut | 1983-04-28 | — | — | WO | disclosed |
| US-4212980-A | REVERSAL OF AMNESIA, TREATMENT OF SENILITY | WARNER-LAMBERT COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4212980-A | REVERSAL OF AMNESIA, TREATMENT OF SENILITY | WARNER-LAMBERT COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4212980-A | REVERSAL OF AMNESIA, TREATMENT OF SENILITY | WARNER-LAMBERT COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200206233-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | IDH1, IDH2, IDH3A | CYP19A1 324/4885LTA4H 1969/4885TSHR 4227/4885 |
| US-20110195999-A1 | NOVEL ANTIFUNGAL AGENT CONTAINING HETEROCYCLIC COMPOUND | ERG28, CYP51A1, XPO1 | CYP19A1 1812/4885LTA4H 1046/4885TSHR 3875/4885 |
| US-20090227799-A1 | Novel Antimalarial Agent Containing Heterocyclic Compound | XPO1, THPO, G6PD | CYP19A1 3015/4885LTA4H 1912/4885TSHR 3836/4885 |
| US-20070105943-A1 | Novel antifungal agent containing heterocyclic compound | ERG28, DPM1, CYP51A1 | CYP19A1 1952/4885LTA4H 1115/4885TSHR 3952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.