Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16812971 | 0.87 | ALDH1A1 (0.62) | ALDH1A1KDM4ESMN1; SMN2HPGDCHRM4 | |
| SCHEMBL16812979 | 0.87 | CHRM4 (0.59) | ALDH1A1HPGDADORA3CHRM4DRD2 | |
| SCHEMBL16812977 | 0.86 | GABRA1 (0.51) | ALDH1A1KDM4ESMN1; SMN2LMNAHPGD | |
| SCHEMBL16812984 | 0.84 | CNR1 (0.47) | KDM4ESMN1; SMN2LMNAADORA3PTGS2 | |
| SCHEMBL16812974 | 0.83 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2MAPTPARP1 | |
| SCHEMBL16813010 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAHPGDCHRM4 | |
| SCHEMBL16796608 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDCHRM4DRD2 | |
| SCHEMBL16813047 | 0.82 | PDE9A (0.42) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL16812999 | 0.81 | GSK3B (0.44) | ALDH1A1LMNAABCG2KMT2ANPC1 | |
| SCHEMBL16813001 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2ADORA3TNKSPARP1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088565-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |