Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.86 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.86 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.69 |
| ▸ | APEX1 | P27695 | 1/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.69 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.63 |
| ▸ | TUBB | P07437 | 5/20 | 0.63 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.63 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.63 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.63 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.63 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Penduletin SCHEMBL30823992 | 0.92 | ABCB1 (1.00) | ABCB1ABCG2POLBKDM4ECYP3A4 | |
| Penduletin SCHEMBL2217068 | 0.92 | ABCB1 (1.00) | ABCB1ABCG2POLBKDM4ECYP3A4 | |
| SCHEMBL1683355 | 0.91 | TUBB4A (0.76) | ABCB1ABCG2POLBCYP3A4CYP2D6 | |
| SCHEMBL29598018 | 0.91 | TUBB4A (0.76) | ABCB1ABCG2POLBCYP3A4CYP2D6 | |
| SCHEMBL28095527 | 0.90 | ABCG2 (0.70) | ABCB1ABCG2POLBMAPTMEN1 | |
| SCHEMBL2727281 | 0.88 | ABCG2 (0.83) | ABCB1ABCG2POLBKDM4ECYP3A4 | |
| Chrysosplenol C SCHEMBL4742072 | 0.88 | ABCG2 (0.73) | ABCB1ABCG2POLBMAPTMEN1 | |
| SCHEMBL2928366 | 0.88 | XDH (0.78) | ABCB1ABCG2POLBKDM4EAPEX1 | |
| SCHEMBL1664156 | 0.86 | ABCG2 (0.76) | ABCB1ABCG2POLBKDM4ECYP3A4 | |
| 3,6-Dimethoxy Kaempferol SCHEMBL30707828 | 0.86 | TUBB4A (0.83) | ABCB1ABCG2POLBKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1698325-B1 | Compositions containing amines and use thereof | JOHNSON & JOHNSON CONSUMER (US) | 2016-07-20 | — | — | EP | disclosed |
| US-8834943-B2 | Compositions containing amines and use thereof | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-8278359-B2 | Compositions containing amines and use thereof to treat acne or reduce the appearance of oil or pores on the skin | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2012-10-02 | — | — | US | disclosed |
| EP-2054046-B1 | COMPOSITIONS CONTAINING CHALCONES AND USE THEREOF | JOHNSON & JOHNSON CONSUMER (US) | 2012-09-26 | — | — | EP | disclosed |
| US-8221046-B2 | Compositions containing amines and use thereof | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-8163313-B2 | Compositions containing amines and use thereof | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| US-20110091586-A1 | COMPOSITIONS CONTAINING AMINES AND USE THEREOF | KENVUE BRANDS LLC | 2011-04-21 | — | — | US | disclosed |
| EP-2248526-A1 | Compositions containing an extract of asparagus and use thereof | Johnson & Johnson Consumer Companies, Inc. (US) | 2010-11-10 | — | — | EP | disclosed |
| US-20100279987-A1 | COMPOSITIONS CONTAINING CHALCONES AND USE THEREOF | SALIOU CLAUDE | 2010-11-04 | — | — | US | disclosed |
| US-7781410-B2 | Compositions containing chalcones and use thereof | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| US-20050238612-A1 | Gingko containing formulations for the improvement of skin radiance | JOHNSON & JOHNSON CONSUMER FRANCE S.A.S. (FR) | 2005-10-27 | — | — | US | disclosed |
| EP-1543822-A1 | Soy containing formulations for the improvement of skin radiance | Johnson & Johnson Consumer France SAS (FR) | 2005-06-22 | — | — | EP | disclosed |
| EP-1543823-A1 | Gingko containing formulations for the improvement of skin radiance | Johnson & Johnson Consumer France SAS (FR) | 2005-06-22 | — | — | EP | disclosed |
| EP-1100516-B1 | EXTRACTS OF FEVERFEW (TANACETUM PARTHENIUM) AGAINST INFLAMMATORY DISORDERS | JOHNSON & JOHNSON CONSUMER FR (FR) | 2005-03-23 | — | — | EP | disclosed |
| WO-2004112819-A1 | COMPOSITIONS AND METHODS OF TREATMENT COMPRISING PLANT EXTRACTS | GELSTAT CORPORATION (US) | 2004-12-29 | — | — | WO | disclosed |
| US-20040105905-A1 | Method for the topical treatment and prevention of inflammatory disorders and related conditions using extracts of feverfew (Tanacetum parthenium) | CALLAGHAN THERESA (NL) | 2004-06-03 | — | — | US | disclosed |
| US-20030077343-A1 | Composition containing feverfew extract and use thereof | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2003-04-24 | — | — | US | disclosed |
| US-20030003170-A1 | Method for the topical treatment and prevention of inflammatory disorders and related conditions using extracts of feverfew (Tanacetum parthenium) | CALLAGHAN THERESA (NL) | 2003-01-02 | — | — | US | disclosed |
| US-20020182166-A1 | Composition containing feverfew extract and use thereof | CHENANGO ZERO LLC | 2002-12-05 | — | — | US | disclosed |
| US-6410062-B1 | Method for the topical treatment and prevention of inflammatory disorders and related conditions using extracts of feverfew (Tanacetum parthenium) | JOHNSON & JOHNSON CONSUMER FRANCE SAS I3540 (FR) | 2002-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110091586-A1 | COMPOSITIONS CONTAINING AMINES AND USE THEREOF | H1-0, HRH3, C5 | ABCB1 3097/4885ABCG2 1465/4885POLB 2353/4885 |
| US-20100279987-A1 | COMPOSITIONS CONTAINING CHALCONES AND USE THEREOF | CYP17A1, HSD17B7, CUTA | ABCB1 470/4885ABCG2 937/4885POLB 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.