Chrysosplenol C

Chrysosplenol C

SCHEMBL4742072

COc1cc(-c2oc3cc(OC)c(O)c(O)c3c(=O)c2OC)ccc1O

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 3/20 0.73
TUBB4A P04350 5/20 0.71
TUBB P07437 5/20 0.71
TUBA3C P0DPH7 5/20 0.71
TUBA1B P68363 5/20 0.71
TUBA4A P68366 5/20 0.71
TUBB4B P68371 5/20 0.71
TUBB3 Q13509 5/20 0.71
TUBB2A Q13885 5/20 0.71
TUBB8 Q3ZCM7 5/20 0.71
TUBA3E Q6PEY2 5/20 0.71
TUBA1A Q71U36 5/20 0.71
TUBA1C Q9BQE3 5/20 0.71
TUBB6 Q9BUF5 5/20 0.71
TUBB2B Q9BVA1 5/20 0.71
TUBB1 Q9H4B7 5/20 0.71
MEN1 O00255 2/20 0.71
KMT2A Q03164 2/20 0.71
POLB P06746 1/20 0.71
MAPT P10636 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2928366 0.93 XDH (0.78) ABCG2TUBB4ATUBBTUBA3CTUBA1B
Chrysosplenol B SCHEMBL29558792 0.93 ABCG2 (0.78) ABCG2TUBB4ATUBBTUBA3CTUBA1B
Chrysosplenol B SCHEMBL2369883 0.93 ABCG2 (0.78) ABCG2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL13560795 0.90 TUBB4A (0.86) ABCG2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL29649084 0.90 TUBB4A (0.86) ABCG2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL30082748 0.89 ABCG2 (0.74) ABCG2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL1683376 0.88 ABCB1 (0.86) ABCG2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL1683355 0.86 TUBB4A (0.76) ABCG2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL29598018 0.86 TUBB4A (0.76) ABCG2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL17620251 0.85 ABCG2 (0.77) ABCG2TUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110261206-B Method for flaking karyotype analysis of large-leaf chrysosporium 中南民族大学 2022-03-08 CN disclosed
CN-110379462-B Method for assembling Chinese Jinyao chloroplast genome sequence based on Illumina technology 中南民族大学 2021-11-26 CN disclosed
CN-110274865-B Method for calculating genome size of Chrysosplenium plant 中南民族大学 2021-09-17 CN disclosed
CN-110379462-A A method of based on the golden waist Chloroplast gene sequence of Illumina Technical form China 中南民族大学 2019-10-25 CN disclosed
CN-110274865-A A method of calculating golden waist platymiscium Genome Size 中南民族大学 2019-09-24 CN disclosed
CN-110261206-A A kind of flaking method of great Ye gold waist chromosome karyotype analysis 中南民族大学 2019-09-20 CN disclosed
EP-2003968-A2 COMPOSITIONS AND METHODS TO ADD VALUE TO PLANT PRODUCTS, SO INCREASING THE COMMERCIAL QUALITY, RESISTANCE TO EXTERNAL FACTORS AND POLYPHENOL CONTENT THEREOF Leschot Sanhueza, Andres Antonio (CL) 2008-12-24 EP disclosed
WO-2008100977-A2 CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS N.V. ORGANON (NL) 2008-08-21 WO disclosed
WO-2007110801-A2 COMPOSITIONS AND METHODS TO ADD VALUE TO PLANT PORDUCTS, INCREASING THE COMMERCIAL QUALITY, RESISTANCE TO EXTERNAL FACTORS AND POLYPHENOL CONTENT THEREOF LESCHOT SANHUEZA ANDRES ANTONI (CL) 2007-10-04 WO disclosed
US-20070232495-A1 Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof NAPPA ALVARO O 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232495-A1 Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof C5, PNN, NQO1 ABCG2 3004/4885TUBB4A 1472/4885TUBB 695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.