Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.71 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.71 |
| ▸ | TUBB | P07437 | 2/20 | 0.71 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.71 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.71 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.71 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.71 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.71 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.71 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.71 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.71 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.71 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.71 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.71 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chrysosplenol C SCHEMBL4742072 | 0.93 | ABCG2 (0.73) | XDHMEN1POLBMAPTKMT2A | |
| Chrysosplenol D SCHEMBL11133546 | 0.93 | ALOX5 (0.83) | XDHMEN1POLBMAPTKMT2A | |
| Chrysosplenol D SCHEMBL29359614 | 0.93 | ALOX5 (0.83) | XDHMEN1POLBMAPTKMT2A | |
| SCHEMBL29024597 | 0.91 | ALOX5 (0.76) | XDHMEN1POLBMAPTKMT2A | |
| Axillarin SCHEMBL29929648 | 0.88 | XDH (1.00) | XDHMEN1POLBMAPTKMT2A | |
| SCHEMBL1683376 | 0.88 | ABCB1 (0.86) | XDHMEN1POLBMAPTKMT2A | |
| Axillarin SCHEMBL29929599 | 0.88 | XDH (1.00) | XDHMEN1POLBMAPTKMT2A | |
| Axillarin SCHEMBL1155670 | 0.88 | XDH (1.00) | XDHMEN1POLBMAPTKMT2A | |
| SCHEMBL8656946 | 0.87 | ALOX5 (0.75) | XDHMEN1POLBMAPTKMT2A | |
| SCHEMBL29598018 | 0.86 | TUBB4A (0.76) | XDHMEN1POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |