Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1684159 | 0.75 | GPR84 (0.36) | HTR1A | |
| SCHEMBL1684162 | 0.75 | GPR84 (0.35) | — | |
| SCHEMBL28819880 | 0.65 | GABRA1 (0.46) | ALDH1A1MAPTGABRA1GABRG2GABRB3 | |
| Ethane SCHEMBL2948593 | 0.65 | HTR2B (0.34) | MAPTMEN1KMT2A | |
| SCHEMBL1684143 | 0.65 | RIPK1 (0.42) | ALDH1A1MPOCDK4CCND1MEN1 | |
| SCHEMBL1684122 | 0.64 | RIPK1 (0.43) | MPOGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2951301 | 0.61 | MMP1 (0.39) | ALDH1A1GAAMAOBMAPT | |
| SCHEMBL1684142 | 0.60 | RIPK1 (0.43) | ALDH1A1MAPTGABRA1GABRG2GABRB3 | |
| SCHEMBL4915074 | 0.59 | GABRA1 (0.46) | ALDH1A1HTR1AMAPTGABRA1GABRG2 | |
| SCHEMBL27794946 | 0.58 | TSHR (0.61) | HTR1AMPOKMT2ASLC6A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041512-A2 | COMPOSITIONS AND METHODS FOR TREATING MLV-INFECTION, AND PREVENTING AND TREATING MLV-INITIATED DISEASES | EMORY UNIVERSITY (US) | 2011-04-07 | — | — | WO | disclosed |