Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 7/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | MC3R | P41968 | 9/20 | 0.40 |
| ▸ | MC4R | P32245 | 7/20 | 0.40 |
| ▸ | MC5R | P33032 | 8/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1684165 | 0.95 | OPRM1 (0.40) | MPOSLC6A4OPRM1ACHESNCA | |
| SCHEMBL1684143 | 0.83 | RIPK1 (0.42) | MPOSLC6A4 | |
| SCHEMBL1684118 | 0.82 | TDO2 (0.36) | OPRM1ACHE | |
| SCHEMBL1684122 | 0.81 | RIPK1 (0.43) | MPOSLC6A4 | |
| SCHEMBL1684139 | 0.80 | TDO2 (0.40) | — | |
| SCHEMBL2951128 | 0.72 | GABRA1 (0.57) | — | |
| SCHEMBL1684142 | 0.72 | RIPK1 (0.43) | — | |
| SCHEMBL1684138 | 0.72 | MPO (0.37) | MPOSLC6A4 | |
| SCHEMBL1684176 | 0.70 | GABRA1 (0.36) | MPOSLC6A4 | |
| SCHEMBL2945211 | 0.66 | GABRA1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041512-A2 | COMPOSITIONS AND METHODS FOR TREATING MLV-INFECTION, AND PREVENTING AND TREATING MLV-INITIATED DISEASES | EMORY UNIVERSITY (US) | 2011-04-07 | — | — | WO | disclosed |